Week 6 NFL Parlay Picks: Geno Goes Off Again

Geno Smith's breakout season could continue to gain momentum in Week 6, facing a Cardinals defense that can't seem to stop anyone. See why our NFL parlay picks are backing Seattle's QB to help push the total — and the rest of our best values to bundle.

Oct 14, 2022 • 14:59 ET • 4 min read
Geno Smith Seattle Seahawks NFL parlay picks
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Week 6 of the NFL season sees the first bye weeks coming into play, as the Lions, Texans, Raiders, and Titans will all sit this Sunday out.

Though there will be two fewer games on the wagering slate, there are still several strong sides to consider. Here are our NFL parlay picks for Week 6. 

Week 6 NFL parlay picks

Click on each pick to jump to the full analysis.

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PARLAY: Bengals vs. Saints Under 43.5 (-110) + Jets +7.5 (-115) = +257 at FanDuel

Bengals vs Saints Under 43.5 (-110)

Considering what transpired at the Caesars Superdome last week — a 39-32 Saints-over-Seahawks shootout — this total seems too low at first glance. But further investigation reveals that the Under should prevail.

The Bengals have been one of the least efficient offenses in football this year, ranking 29th in yards per play (4.8). Joe Mixon is averaging a meager 3.1 yards per carry, and Ja’Marr Chase has underwhelmed by averaging fewer than 70 receiving yards per game one year after breaking the rookie record with 1,455 receiving yards. 

Quarterback Joe Burrow has had a rough campaign, as he’s been sacked 19 times, making the Bengals’ offensive line the fifth-worst in football. New Orleans’ stoppers were likely fatigued from a trip to London the previous week when they gave up as much yardage as they did to Seattle. That won’t be the case this time around in the second of back-to-back home games. 

Meanwhile, Jameis Winston (back/ankle) is expected to return under center for the Saints following two missed games. He continues to be turnover-prone in his eighth year in the NFL, as he’s tossed five interceptions in only three contests. That spells trouble against a Cincinnati defense that’s already picked off opposing quarterbacks five times this season while allowing the fourth-lowest opponent passer rating (72.1). 

With wide-outs Chris Olave (concussion), Michael Thomas (foot), and Jarvis Landry (ankle) all on the injury report for New Orleans, their offense could be in deep trouble on Sunday.

Jets +7.5 (-115)

One has to wonder if the Jets are ever going to get some respect this season. It’s been ugly at times, but “Gang Green” has played to a 3-2 record, and are fresh off their biggest win in years — a 40-17 drubbing of the Dolphins. Though Lambeau Field is never an easy destination for visiting teams, New York should hold its own against the Packers this week.

The Jets’ defense has been better than many expected heading into this season, ranking ninth in opponent yards per play (5.2) and 11th in opponent passer rating (81.2). By contrast, Green Bay’s stoppers rank 15th (5.5) and 25th (100.2) in those respective categories. New York has also out-intercepted the Packers 7-1. 

“Gang Green” has kept a lid on opposing running backs too, ranking fifth with 4.0 yards allowed per rush. Green Bay is 24th with 4.8 yards allowed per rush this year. Rookie running back Breece Hall could be in for a big day on the ground, which would ease the burden for Zach Wilson against an Aaron Rodgers-led Pack attack. 

New York has an outside shot at beating a Green Bay team that just lost to the Giants in London in Week 5, and needed a last-second field goal to beat Bailey Zappe and the Patriots the week before that. Getting over a touchdown with them is too good an opportunity to pass up. 

PARLAY: Ravens vs. Giants Over 45 (-110) + Cardinals vs. Seahawks Over 50.5 (-105) = +273 at DraftKings

Ravens vs Giants Over 45 (-110)

Two of the best rushing offenses in football meet two of the worst run-stopping defenses as the Ravens visit the Giants on Sunday. Points should be produced early and often here.

Lamar Jackson and Co. are averaging 5.4 yards per rush, and the same can be said for the Saquon Barkley Show in New York, putting them in a tie for the second-most efficient ground game in football. The defenses are tied for 25th in yards allowed per rushing attempt at 5.0 through five weeks. 

The Giants’ troubles on defense figure to be amplified following the trip to London in Week 5. The Vikings’ defense didn’t look great in a 29-22 win over the Bears, and the Saints’ stoppers were even worse in a 39-32 triumph over the Seahawks. 

If Jackson isn’t hammering “Big Blue” on the ground, he’ll be going to the air with success with two reliable targets in Devin Duvernay and Mark Andrews to turn to. 

Cardinals vs Seahawks Over 50.5 (-105) 

The skies should be clear in Seattle this Sunday, paving the way for a track meet to develop as the Cardinals make their annual trek to take on the Seahawks. 

Both stoppers in this scrimmage are soft, as Arizona enters with the 10th-worst defense by yards allowed per play (5.9) and points allowed per game (24.6). Seattle is even worse, as it’s last in yards allowed per play (6.6) and 31st in points allowed per game (30.8). 

The Cardinals’ pass defense has been particularly porous, allowing 7.4 yards per attempt, 24th in the NFL. Geno Smith has come into his own under center for the Seahawks, averaging 9.2 yards per attempt over his last three games with a 7-1 touchdown-interception ratio. 

Seattle has been bowled over by opposing running games, ranking dead-last in rushing yards allowed per game (170.2). Kyler Murray should be able to move the chain with his legs as well as his arm on Sunday.

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