Christian McCaffrey Odds, Projections & SGP for Seahawks vs 49ers

Tonight’s NFC West showdown in Santa Clara carries massive playoff seeding implications, and our computer projections have you covered on how to bet Christian McCaffrey in this Week 18 finale.

Trevor Knapp - Betting Analyst at Covers.com
Trevor Knapp • Betting Analyst
Jan 3, 2026 • 12:20 ET • 4 min read
Christian McCaffrey San Francisco 49ers NFL
Photo By - Imagn Images. San Francisco 49ers running back Christian McCaffrey (23).

The No. 1 seed in the NFC will be decided tonight as the San Francisco 49ers host the Seattle Seahawks.

Christian McCaffrey has been on an absolute heater over the last two games, and all eyes will be on the superstar running back at Levi’s Stadium.

Let's dive into the best Christian McCaffrey odds to target ahead of kickoff, according to our latest NFL player prop projections.

Christian McCaffrey projections for Seahawks vs 49ers

Market Proj. Odds Value
Rushing yards
(67.5)
67.66 Over 67.5
-114
A
Receptions
(5.5)
4.64 Under 5.5
-160
A
Receiving yards
(43.5)
43.1 Under 43.5
-114
B+
Anytime touchdown 0.86 Over 0.5
-165
C

Fresh off 100+ yard rushing outings in two consecutive games, CMC should eclipse his rushing O/U tonight against the Seahawks.

The 49ers running back is expected to be contained through the air, however, as our computer anticipates McCaffrey failing to eclipse both his receptions and receiving yards totals.

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Christian McCaffrey same-game parlay for Seahawks vs 49ers

Over 67.5 rushing yards

Under 43.5 receiving yards

Under 5.5 receptions

Our 3-leg SGP has McCaffrey cashing the Over on his rushing total while being limited through the air against Seattle.

There’s also a 30% profit boost available at FanDuel for a 3+ leg SGP on tonight's game, which would bump this parlay up to +345 if applied.


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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Trevor Knapp - Covers
Betting Analyst

Trevor joined the Covers content team as a publishing editor in early 2022. Growing up in Vancouver, he studied Broadcast and Online Journalism at the British Columbia Institute of Technology (BCIT), and interned with TSN and Sportsnet Radio while also writing for the Daily Hive.

An avid bettor of the MLB, NFL, and CFL, Trevor advises his fellow sports bettors to leave their hearts at the door and not hesitate to fade their favorite team. It's a strategy he follows regularly as an apathetic Indianapolis Colts and Toronto Blue Jays fan.

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