Virginia Tech and No. 13 South Carolina will open their respective seasons in a primetime slot at a neutral venue in Atlanta.
Big expectations abound for the Gamecocks, who enter this season predicted to finish fifth in the SEC by the media but with their eyes on even greater achievements.
As for Virginia Tech, the Hokies face a pivotal season regarding the future of head coach Brent Pry, who enters his fourth year looking to finally make a leap.
My Virginia Tech vs. South Carolina predictions break it down here as I bring you my college football picks when the two teams meet Sunday, August 31.
Virginia Tech vs South Carolina prediction
Virginia Tech vs South Carolina best bet: Virginia Tech +7.5 (-110 at FanDuel)
Rust, new coordinators on both sides, and a battle in the trenches point to a tight matchup. With that in mind, grabbing either team at more than a touchdown feels like value. I’m backing the Hokies to cover.
Virginia Tech’s offensive line is still a question mark against South Carolina’s disruptive front, but that very struggle could help keep the game close. The Hokies will try to control the ball, bleed the clock, and lean on QB Kyron Drones to extend plays on the edge. The line has been reworked, with a couple of returners but enough new pieces that consistency may come slowly.
South Carolina’s offense has upside, but not right away. The Gamecocks lost three starters from the offensive line, and while they may hold a physical edge, it will take time to gel. Pair that with a transition to new offensive coordinator Mike Shula’s system, and a slow start is likely.
Continuity leans Virginia Tech’s way. South Carolina’s long-term potential is clear, but in this opener the Hokies are better positioned to hang around and keep it close.
Virginia Tech vs South Carolina same-game parlay
For large portions of the game, both offenses struggle to get going as Virginia Tech’s offensive line faces physical issues and South Carolina’s offense adjusts to a new system.
Eventually, though, South Carolina’s talented backfield takes over, and the attrition war tilts in the Gamecocks’ favor.
We paired that angle with Rahsul Faison to score. The talented tailback ran for eight touchdowns last season, and behind an offensive line that should generate more push as the game wears on, he’s well-positioned to open his account here.
Bet this Virginia Tech vs. South Carolina SGP now at FanDuel!
Our deep-ball SGP: Keeping It On the Ground
- Kryon Drones Under 186.5 passing yards
I don’t expect much from Drones through the air, largely because volume won’t be on his side. Pressure is one factor, but Virginia Tech will also look to shorten the game with plenty of designed runs for their quarterback.
Virginia Tech vs South Carolina odds
- Spread: Virginia Tech +7.5 (-110) | South Carolina -7.5 (-110)
- Moneyline: Virginia Tech +230 | South Carolina -285
- Over/Under: Over 51.5 (-115) | Under 51.5 (-105)
Virginia Tech vs South Carolina trend to know
Virginia Tech has hit the 1H Moneyline in 7 of their last 9 games (+8.35 Units / 53% ROI). Find more college football betting trends for Virginia Tech vs South Carolina.
How to watch Virginia Tech vs South Carolina
Location | Mercedes-Benz Stadium, Atlanta, GA |
Date | Sunday, August 31, 2025 |
Kickoff | 3:00 p.m. ET |
TV | ESPN |
Virginia Tech vs South Carolina latest injuries
Virginia Tech vs South Carolina weather
Monitor gametime conditions with our College football weather info.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.