Utah vs West Virginia Prediction, Picks & Odds for September 27 — College Football Week 5

The Utes struggled against Texas Tech, but our Utah vs. West Virginia predictions expect a much better performance in Morgantown this weekend.

Jeremy Jones - Contributor at Covers
Jeremy Jones • Betting Analyst
Sep 25, 2025 • 14:11 ET • 4 min read

NCAAF

Match starts: 47 hrs
WVU
46 %
UTAH
54 %
EXPERT PICK - SPREAD
Utah -12.5 (-110) Utah -12.5 (-110)
Read Analysis
Utah Utes Big 12 college football
Photo By - Imagn Images. Utah quarterback Devon Dampier hands the ball off to running back Wayshawn Parker.

Two teams that were demolished at home last week in their Big 12 openers will be looking to bounce back when the Utah Utes travel to Morgantown to take on the West Virginia Mountaineers.

One of those losses was more indicative of who their team is than the other, and that should show this week. Find out who I like in my Utah vs. West Virginia predictions and college football picks for Saturday, September 27.

Utah vs West Virginia prediction

Utah vs West Virginia best bet: Utah -12.5 (-110)

The Utah Utes were ranked 16th in the nation before getting smoked at home last weekend by Texas Tech. However, I think that was more about how good the Red Raiders are than how bad the Utes are. This Utah defense is still very good. 

They held UCLA to 10 points and Wyoming to six points — both games on the road. Meanwhile, the West Virginia Mountaineers only scored 10 points in each of their games against Ohio and Kansas. Neither of those defenses is anywhere near the talent of this Utah defense. 

The Mountaineers did have an impressive 31-24 win over Pitt in between those two games, but that's a heated rivalry game, and sometimes you have to throw numbers and talent out the window in those cases. The other two performances are more likely the real West Virginia. 

WVU quarterback Nicco Marchiol is questionable, and three running backs may not suit up for the Mountaineers. I just don’t see how they can score enough to keep this game close, even if Utah's offensive struggles continue.

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Utah vs West Virginia odds

  • Spread: Utah -12.5 | West Virginia +12.5
  • Moneyline: Utah -500 | West Virginia +375
  • Over/Under: Over 47.5 | Under 47.5

Utah vs West Virginia trend to know

Utah has cashed the Under in four of its last six road games. Find more college football betting trends for Utah vs West Virginia.

How to watch Utah vs West Virginia

Location Milan Puskar Stadium, Morgantown, WV
Date Saturday, September 27, 2025
Kickoff 3:30 p.m. ET
TV FOX

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Jeremy Jones - Covers
Betting Analyst

Jeremy Jones was born and raised in Lexington, Kentucky and has been a massive Wildcats fans since the moment he came into the world. He wrote his first sports article at the tender age of 11 after attending a local AHL hockey game, and a few years later was writing professionally for sites such as Sports Rants, BetAmerica, and TwinSpires.

Jeremy holds a Masters in Sports Administration from Eastern Kentucky University and utilizes all seven betting options available in Kentucky to shop for odds and promos and find the greatest EV in every wager he places.

His best piece of sports betting advice is to stick to consistent unit sizes for every wager. He acknowledges there will occasionally be a bet that has a huge EV and you can play multiple units in one bet, but cautions against raising your unit size, because you can quickly lose all your winnings if you hit a minor cold streak.

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