College Football Over/Under Picks: Week 4

Chris Vasile - Betting Analyst at Covers.com
Chris Vasile • Betting Analyst 13+ years betting experience
Updated: Sep 24, 2026 , 01:00 PM ET • 4 min read

Chris Vasile expects points when UCLA visits Maryland, while a dominant Penn State defense headlines his three favorite college football totals for Week 4.

Maryland Terrapins quarterback Malik Washington (7) passes the football.
Photo By - Reuters Connect. Maryland Terrapins quarterback Malik Washington (7) passes the football.

Week 4 is loaded with ranked matchups and conference showdowns, but one of my favorite college football Over/Under picks on the entire board comes from UCLA's trip to Maryland.

The Bruins have been running teams over, the Terps can sling it, and I think 56.5 is asking too little from two offenses that match up well with what the other defense gives away.

Read below for more college football picks for Week 4. 

Week 4 college football Over/Under picks

Matchup Kalshi
UCLA UCLA
vs
Maryland Maryland
o56.5
Wake Forest Wake Forest
vs
Louisville Louisville
o57.5
Wisconsin Wisconsin
vs
Penn State Penn State
u44.5

Percentages courtesy of Kalshi, one of the best prediction market apps.

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Expert Week 4 CFB Over/Under picks

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UCLA vs Maryland: Over 56.5

UCLA's ground game has been ridiculous, with Wayne Knight averaging 8.85 yards per carry and scoring eight times, but Maryland has the offense to make this a back-and-forth game.

Malik Washington has thrown for 706 yards over his last two starts alone, including 359 against Virginia Tech, and now gets a UCLA defense that just allowed Purdue to score 38.

The Bruins should have success controlling the game on the ground, but Washington gives Maryland the firepower to keep answering. I have this closer to the low 60s than 56.5.

Wake Forest vs Louisville: Over 57.5

Louisville isn't just scoring a lot — it's making defenses pick their poison. Lincoln Kienholz has six passing touchdowns, four more on the ground, and hasn't thrown an interception, while the Cardinals just ran for 265 yards against SMU. The problem is Louisville allowed 479 yards and 31 points in that same game.

That combination is perfect for an Over.

Wake doesn't have to match Louisville score for score; it just needs to take advantage of a defense giving up yards. If Wake gets into the 20s, Louisville can push this past 57.5.

Wisconsin vs Penn State: Under 44.5

Colton Joseph threw for 362 yards in Wisconsin's 54-point explosion against Eastern Michigan, but this is where we find out how much of that was opponent-driven. Penn State is allowing just 7.3 points per game, and Wisconsin's offense now has to sustain drives against a defense that's been excellent at getting off the field.

The Badgers can help the Under themselves with a defense allowing fewer than 300 yards per game.

If Penn State gets ahead, I expect Wisconsin to struggle to answer while the Nittany Lions bleed the game away on the ground.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Vasile Covers.com
Betting Analyst

Chris Vasile is a betting analyst with over 13 years of experience breaking down soccer betting markets, with additional coverage across the WNBA and NFL. He focuses on finding numbers that are slow to adjust — whether it’s due to scheduling spots, player usage, or recent form — and explaining why a line is worth playing. His work has appeared across major betting and sports media platforms, including Covers, VSiN, BetMGM Network, and SportsGrid, where he’s delivered sharp analysis on both mainstream and niche markets. At Covers, he contributes to major tournament coverage and daily betting content, with a particular focus on soccer. He also runs the Game Day Wagers YouTube channel, where he shares daily picks and betting insights tailored for serious bettors.

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