Middle Tennessee vs Delaware Prediction, Picks & Odds for October 22 — College Football Week 9

Delaware piles on the points against a suspect Middle Tennessee defense thanks to the continued improved play from QB Nick Minicucci.

Andrew Caley - Senior Betting Analyst at Covers.com
Andrew Caley • Senior Betting Analyst
Oct 22, 2025 • 11:06 ET • 4 min read

NCAAF

Match starts: 5 hrs
DEL
63 %
MTU
37 %
EXPERT PICK - PROP
Delaware o32.5  (-115) Delaware o32.5 (-115)
Read Analysis
Nick Minicucci Delaware Fightin' Blue Hens NCAA College Football
Photo By - Imagn Images. Delaware QB Nick Minicucci throws the ball in college football action.

Move over mid-week MACtion! We’ve now got the crazy C-USA to carry the early week college football schedule, as the Delaware Fightin' Blue Hens host the Middle Tennessee Blue Raiders in a battle of the blues.

It’s been a tough season for the Blue Raiders, who have just one win, while the Blue Hens are trying to inch closer to bowl eligibility in their first season in the FBS.

My Middle Tennessee vs. Delaware predictions and college football picks explain why the Hens will be the cock of the Walk on Wednesday, October 22.

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Middle Tennessee vs Delaware prediction

Middle Tennessee vs Delaware best bet: Delaware team total Over 32.5 (-115)

Despite back-to-back losses, the 3-3 Delaware Fightin' Blue Hens’ first foray into FBS football hasn’t gone too badly. They are led by quarterback Nick Minicucci and a defense that is one of the more underrated units in the Group of Five.

Meanwhile, it’s been a tough go for the Middle Tennessee Blue Raiders, with their lone win coming in a one-point victory over Nevada back on Sept. 13. And the numbers aren’t pretty. The Blue Raiders rank 122nd in EPA per play on offense and 118th in EPA per play on defense.

They’ve really been torched by opposing QBs, ranking 126th in opponent EPA per dropback and 96th in defensive success rate on dropbacks. So, slowing down an ever-improving Minicucci looks like a tough task.

Minicucci has thrown for 1,801 yards at 7.6 yards per attempt while completing 64.4% of his passes so far this season. He’s also thrown for at least 300 yards in three of his last five games.

Minicucci has helped the Blue Hens average 29 points per game over their last four, topping 38 twice in that stretch. I like them to make it three times in five games against a Middle Tennessee defense that leaks like a sieve. 

Middle Tennessee vs Delaware same-game parlay

Minicucci’s favorite target this season has been Kyre Duplessis. The 5-foot-11 wideout already has 28 catches for 430 yards. However, he has only found the end zone twice this season. That changes this week. 

We’ve noted how Middle Tennessee's pass defense is bad, but the team has also allowed opponents to throw 14 touchdown passes. That ranks 115th in the country. 

Not to beat down on the Blue Raiders, but things just ain’t great with this team. Bad offense plus bad defense equals slow starts. Middle Tennessee ranks 105th in opponent first-half scoring, giving up an average of 17 points in the opening half.

I like Delaware to get off to a good start, so round this SGP out with the Blue Hens to cover the 6.5-point first-half spread.

Middle Tennessee vs Delaware SGP

  • Delaware team total Over 32.5
  • Kyre Duplessis anytime TD
  • Delaware -6.5 first half

Our deep-ball SGP: Singin' the blues

The place you should attack Delaware is through the air, and big-bodied Nahzae Cox is the Blue Raiders' best threat to score in the red zone, already grabbing four touchdowns this season. 

Middle Tennessee vs Delaware SGP

  • Delaware team total Over 32.5
  • Kyre Duplessis anytime TD
  • Delaware -6.5 first half
  • Nahzae Cox anytime TD

Middle Tennessee vs Delaware odds

  • Spread: Middle Tennessee +9.5 | Delaware -9.5
  • Moneyline: Middle Tennessee +270 | Delaware -395
  • Over/Under: Over 55.5 | Under 55.5

Middle Tennessee vs Delaware trend to know

Delaware has covered the 1H Spread in 4 of its last 5 games for +2.85 Units and a 50% ROI. Find more college football betting trends for Middle Tennessee vs Delaware.

How to watch Middle Tennessee vs Delaware

Location Delaware Stadium, Newark, DE
Date Wednesday, October 22, 2025
Kickoff 7:30 p.m. ET
TV ESPN2

Middle Tennessee vs Delaware latest injuries

Middle Tennessee vs Delaware weather

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Andrew Caley
Senior Betting Analyst

When his dreams of becoming the next Steve Nash died, all Andrew "Taco" Caley wanted to do was write about sports, something he's been doing at Covers for more than a decade. A Journalism School grad from Holland College in Charlottetown, PEI, Andrew previously worked at The Chronicle Herald and Star Metro, but knew in his heart that his future lay in sports. He began at Covers as a news editor and has now done everything under the sun when it comes to content. His work has been seen on TSN, Sportsnet, VSiN, and CBS. These days Andrew's betting expertise is focused on his favorite teams; the Toronto Blue Jays and Toronto Raptors. He's also an avid college football fan and bettor. He can't be friends with you if you don't appreciate a Service Academy Under. The sportsbook where he does the bulk of his betting is bet365 thanks to its numerous prop betting options and competitive odds. His best advice? Find the balance between the numbers and what you see on the playing field. Then find the best price using multiple books. And don’t ask him where the nickname Taco comes from. It's not an interesting story. Seriously.

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