Few people enjoy antagonizing someone as much as Mississippi Rebels head coach Lane Kiffin enjoys antagonizing the most veteran coach in the SEC.
Without Nick Saban around anymore, Kiffin turns his eyes to LSU Tigers head coach Brian Kelly.
My LSU vs. Mississippi predictions and college football picks expect those choices to backfire on Kiffin on Saturday, September 27.
Our best LSU vs Mississippi SGP for Week 5
Everyone wants to bet this Over. Lane Kiffin told them to on social media because his daughter is dating an LSU linebacker.
Who cares?
That is Kiffin’s shtick.
The reality is, Brian Kelly has beaten Kiffin twice, and in both instances, the Under cashed. Now, LSU is better defined by its defense than at any point in Kelly’s Baton Rouge tenure, so he should lean on it even more.
That has worked so far, with the Tigers’ three FBS games all going Under their totals, and not by a small amount.
Who wants to tell @JonMetler that LSU's three FBS games this year have fallen short of their totals by more than three touchdowns per game? https://t.co/aYPvYFNj6Z
— Douglas Farmer (@D_Farmer) September 25, 2025
Mississippi quarterback Trinidad Chambliss has looked the part so far, but it’s usually around a player’s third genuine appearance that opposing defensive coordinators see why a backup quarterback was a backup to begin with.
If LSU’s Blake Baker sees that, expect the ball to be taken out of Chambliss’s hands.
Fortunately for the Rebels, Kewan Lacy has cleared this prop in three of four games this season. Unfortunately for Mississippi, the running game is not how Kiffin has designed this team to win.
LSU vs Mississippi 3-leg SGP
- LSU moneyline
- Under 54.5
- Kewan Lacy Over 67.5 rushing yards
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