The BYU Cougars are firmly in the Big 12 Championship hunt, and they face a stiff road test on Saturday against the Cincinnati Bearcats.
The Cougars enter this matchup with clear advantages on both sides of the ball, and my BYU vs. Cincinnati predictions expect BYU to pull off the road win.
Read on for my college football picks for Saturday, November 22.
BYU vs Cincinnati prediction
BYU vs Cincinnati best bet: BYU moneyline (-138)
The BYU Cougars is better on both offense and defense, and should beat the Cincinnati Bearcats this Saturday.
The Cougars’ biggest strength is their physical run game, averaging 195 rushing yards per contest behind LJ Martin, who matches up perfectly against a Cincinnati defense allowing 158 rushing yards per game and over 4.0 yards per carry.
BYU’s efficiency on early downs and solid passing offense consistently move the chains, which will keep Cincinnati’s defense on its heels and should open up play-action opportunities for quarterback Bear Bachmeier.
Defensively, BYU is built to shut down what Cincinnati does best. The Cougars allow just 191.5 passing yards per game and only eight passing touchdowns all season, making life difficult for Bearcats quarterback Brendan Sorsby.
Add in BYU’s strong third-down defense (31%), superior turnover production, and overall red-zone efficiency, and the Cougars hold a complete situational edge.
BYU vs Cincinnati same-game parlay
BYU wideout Chase Roberts has cleared his receptions total in three straight games and in six of his previous 10.
Bachmeier might rack up the completions and passing yards, but he’s thrown more than two touchdowns only once in his previous six games.
BYU vs Cincinnati SGP
- BYU moneyline
- Chase Roberts Over 4.5 receptions
- Bear Bachmeier Under 1.5 passing TDs
Our deep-ball SGP: Back to Bachmeier
Bachmeier has thrown for at least 212 passing yards in three of his previous six games and meets a Cincinnati defense allowing 232.5 passing yards per game.
BYU vs Cincinnati SGP
- BYU moneyline
- Chase Roberts Over 4.5 receptions
- Bear Bachmeier Under 1.5 passing TDs
- Bear Bachmeier Over 211.5 passing yards
BYU vs Cincinnati odds
- Spread: BYU -2.5 (-110) | Cincinnati +2.5 (-110)
- Moneyline: BYU -125 | Cincinnati +105
- Over/Under: Over 53.5 (-110) | Under 53.5 (-110)
BYU vs Cincinnati trend to know
BYU is 9-1 in their previous 10 games. Find more college football betting trends for BYU vs Cincinnati.
How to watch BYU vs Cincinnati
| Location | Nippert Stadium, Cincinnati, OH |
| Date | Saturday, November 22, 2025 |
| Kickoff | 8:00 p.m. ET |
| TV | FOX |
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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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