Indiana vs Purdue Prediction, Picks & Odds for Tonight's College Basketball Game

Lamar Wilkerson and the Hoosiers won't go down without a fight against in-state rival Purdue at Mackey Arena tonight.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Feb 20, 2026 • 10:42 ET • 4 min read

NCAAB

Match starts: 8 hrs
IND
60 %
PUR
40 %
EXPERT PICK - SPREAD
Indiana +11.0 (-110) Indiana +11.0 (-110)
Read Analysis
Indiana Hoosiers college basketball Lamar Wilkerson
Photo By - Reuters Connect. Indiana Hoosiers guard Lamar Wilkerson (3) goes to the basket against Purdue.

The No. 7 ranked Purdue Boilermakers host the Indiana Hoosiers in a Big Ten battle on Friday night.

The Hoosiers upset the Boilermakers earlier this year and my Indiana vs. Purdue predictions think they're being spotted too many points tonight.

Here are my best free college basketball picks for this rivalry clash on February 20.

Indiana vs Purdue prediction

Indiana vs Purdue best bet: Indiana +11 (-110)

The Purdue Boilermakers have underperformed at home, going 0-6 ATS in their last six games at Mackey Arena.

The Indiana Hoosiers are more than familiar with the short trip to West Lafayette and beat the Boilermakers 72-67 last month at home. There were no statistical outliers in that game and IU is now 7-2 ATS in the last seven meetings with four outright wins as underdogs. 

Indiana's biggest weakness is rim protection and opponent FT rate. However, the Boilermakers won't be able to take advantage since they sit outside the top 300 in attacking the rim frequency and FT rate.

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Indiana vs Purdue same-game parlay

While I'm betting on Indiana to cover the 11-point spread, the Boilermakers should win outright. They are rated higher on both sides of the floor and are in a revenge and a bounce-back spot following a loss to No. 1 Michigan.

IU ranks just 13th in the Big Ten in rebound rate during conference play. Purdue forward Trey Kaufman-Renn has grabbed double-digit boards in four of his last five games and is coming off a 12-rebound performance against Michigan's elite frontcourt.

Indiana vs Purdue SGP

  • Indiana +11
  • Purdue moneyline
  • Trey Kaufman-Renn Over 9.5 rebounds

Our beyond the arc SGP: Stars shine

Kaufman-Renn also scored 27 points against Michigan and the 2025 All-Big Ten selection is hitting his stride after a slow start to the season. He should torch Indiana's soft interior defense.

Lamar Wilkerson leads IU with 21.2 ppg and has dropped 24+ points in four of his last five games. He scored 19 points with seven boards in that previous meeting against Purdue and was expected to score another seven points per ShotQualityBets.

Indiana vs Purdue SGP

  • Trey Kaufman-Renn Over 14.5 points
  • Trey Kaufman-Renn Over 9.5 rebounds
  • Lamar Wilkerson Over 21.5 points
  • Lamar Wilkerson Over 4.5 rebounds

Indiana vs Purdue odds

  • Spread: Indiana +11 | Purdue -11
  • Moneyline: Indiana +525 | Purdue -750
  • Over/Under: Over 148.5 | Under 148.5

Indiana vs Purdue betting trend to know

The Hoosiers are 5-4 SU and 7-2 ATS in the last nine meetings between these in-state rivals. Find more college basketball betting trends for Indiana vs. Purdue.

How to watch Indiana vs Purdue

Location Mackey Arena, West Lafayette, IN
Date Friday, February 20, 2026
Tip-off 8:00 p.m. ET
TV FOX

Indiana vs Purdue key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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