Georgetown vs Villanova Prediction, Picks & Odds for Tonight's College Basketball Game

The Hoyas have some things to straighten out, but a Big East showdown with the Villanova Wildcats could prove to be another hurdle for Georgetown.

Chris Hatfield - Contributor at Covers.com
Chris Hatfield • Betting Analyst
Jan 21, 2026 • 14:33 ET • 4 min read

NCAAB

Match starts: 3 hrs
VILL
43 %
GTWN
57 %
EXPERT PICK - SPREAD
Villanova -8.5 (-110) Villanova -8.5 (-110)
Read Analysis
Duke Brennan Villanova Wildcats NCAAB
Photo By - Reuters Connect. Villanova Wildcats forward Duke Brennan (24) reacts after dunking the ball.

Villanova and Georgetown meet in an interesting Big East affair.

The Hoyas have been on an abysmal run, and you have to wonder if their season is in danger of completely going off the rails.

They enter this matchup riding a five-game losing streak, though it’s worth noting that three of those defeats were decided by a combined nine points. Now we’ll see if they can provide a much-improved Villanova squad with a stiff challenge.

I break it all down in my Georgetown vs. Villanova predictions & college basketball picks for Tuesday, January 20.

Georgetown vs Villanova prediction

Georgetown vs Villanova best bet: Villanova -8.5 (-110)

My best bet in this matchup are the Villanova Wildcats -8.5. I projected a spread of -10.5, so I see decent value, especially when you factor in the matchup edges Villanova has.

Villanova is simply the more complete team on both ends. Offensively, their profile is built on efficiency through big cut-and-roll and pick-and-pop actions, plus the kind of rebound-and-scramble production that turns “good” possessions into great ones.

It’s particularly troubling that the Georgetown Hoyas allow nearly a point per possession on significant cut-and-roll actions while also being a below-average rebounding team.

Duke Brennan, who is scoring 1.35 points per possession on big cuts and rolls, can have a massive game by exploiting those half-court breakdowns while also being the best offensive rebounder on the floor and generating second chances.

If Georgetown can’t consistently finish possessions with a clean rebound, Villanova will separate without needing to shoot lights out.

On the other end, Villanova’s defense should do a strong job of taking away Georgetown’s main actions. Even though Georgetown doesn’t run it at an elite level, they do get to mid-range at a reasonably high frequency, and Villanova has been excellent at bottling that up, allowing just 0.73 points per possession on mid-range actions this season.

That’s a low-upside scoring path against a disciplined defense, and it becomes even tougher when the game slows into half-court reps.

Tempo should be at a comfortable pace for both teams, which is another quiet plus for the favorite: Villanova can execute in structure, control runs, and keep Georgetown from turning this into a scramble-heavy game on their terms.

I’ll take a team like Villanova with this many edges pretty much every time. This is playable to my projected number of -10.5.

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Georgetown vs Villanova same-game parlay

I expect this to be a Duke Brennan game for the very reasons highlighted in my best bet and I’m consequently taking him to exceed both his rebound total plus points total in my same-game parlay.

As long as he avoids foul trouble, Brennan has a clear cut path to scoring regularly and generating second chances opportunities throughout this game. 

Georgetown vs Villanova SGP

  • Villanova -8.5
  • Duke Brennan Over 11.5 points
  • Duke Brennan Over 10.5 rebounds

Our beyond the arc SGP: Keep an eye on the offense

I see about a point of value on this total so I’m adding the Over to my longshot.

The pace won’t be too terrible and we’ve already mentioned the Villanova offensive advantages. What we’ve failed to mention is although they’ll struggle to generate points from time-to-time, the Hoyas will find some scoring chances at the rim. 

Georgetown vs Villanova SGP

  • Villanova -8.5
  • Duke Brennan Over 11.5 points
  • Duke Brennan Over 10.5 rebounds
  • Over 143.5

Georgetown vs Villanova odds

  • Spread: Georgetown +8.5 (-110) | Villanova -8.5 (-110)
  • Moneyline: Georgetown +350 | Villanova -450
  • Over/Under: Over 143.5 (-110) | Under 143.5 (-110)

Georgetown vs Villanova betting trend to know

Georgetown has hit the Game Total Over in 22 of their last 33 games (+9.90 Units / 27% ROI). Find more college basketball betting trends for Georgetown vs. Villanova.

How to watch Georgetown vs Villanova

Location Finneran Pavilion, Villanova, PA
Date Wednesday, January 21, 2026
Tip-off 7:00 p.m. ET
TV Peacock

Georgetown vs Villanova key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Hatfield - Covers.com
Betting Analyst

Chris has always had a passion for three things: solving problems, sports, and writing. It’s no wonder then that he found himself attracted to the sports betting industry. You can find Chris betting every day. Whether it’s shot prop markets in Champions League Soccer qualifiers or NBA Summer League, he has no offseason. As an EV+ bettor, he especially values the insight gained through a data-driven approach.

His work has been featured on various websites such as SBNation, Rivals, Bleacher Report, and 247Sports. He has appeared on radio outlets such as ESPN 680 and The Sharp 600 podcast. You can listen to his own podcast, “What High School Did You Go To?” on Apple Podcast and Soundcloud.

Chris has carved out a niche as a college basketball originator with massive profitability success in that sport and stresses one piece of advice to sports bettors: exploit edges as broadly as possible and take advantage of them while they last. His preferred sportsbook is bet365 because of the range of markets you can find.

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