Trail Blazers vs Spurs Computer Picks: Our Best Player Prop Projections for Game 2

Aisha Quiñones - Betting Analyst at Covers
Aisha Quiñones • Betting Analyst 12+ years betting experience
Updated: Apr 21, 2026 , 02:15 PM ET • 4 min read

We analyzed Game 2 of the NBA Playoff matchup between the Portland Trail Blazers and San Antonio Spurs, highlighting key player prop opportunities and comparing them to the latest market lines to identify value spots.

Victor Wembanyama Deni Avdija San Antonio Spurs Portland Trail Blazers NBA
Photo By - Reuters Connect. Portland Trail Blazers forward Deni Avdija (8) dribbles against San Antonio Spurs center Victor Wembanyama (1) in the second half.

Our NBA player prop projections are locked in for tonight’s Game 2 showdown between the Portland Trail Blazers and San Antonio Spurs, with the model highlighting several high-value spots across the board.

By breaking down the data and comparing it to current market lines, we’ve pinpointed where the strongest edges appear.

These Trail Blazers vs. Spurs predictions aren’t based on narrative or intuition; they’re driven by the numbers.

If you’re building out your card, here are the model’s top NBA picks for Tuesday, April 21.

Trail Blazers vs Spurs computer picks for Game 2

Blazers Trail Blazers Spurs Spurs
Avdija u23.5 points 
-105
Wembanyama u28.5 points 
-105
Holiday o5.5 assists 
-140
Wembanyama o11.5 rebounds
-115
Henderson o1.5 3-pointers
+115
Fox o5.5 assists
-120

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Trail Blazers Game 2 computer picks

Deni Avdija Under 23.5 points (-105)

Projection: 22.4 points

The Portland Trail Blazers have struggled offensively on the road, ranking as the fourth-lowest scoring team in the league over their last 25 away games.

Over their last five road contests, opposing starting power forwards have managed just 13.0 points per game against the San Antonio Spurs—the fourth-lowest mark in the NBA. That sets up as a difficult spot for Deni Avdija to replicate the offensive output he delivered in Game 1.

🔥 Bet avdija Now at bet365!

Jrue Holiday Over 5.5 assists (-140)

Projection: 6.4 assists

Jrue Holiday has cleared the 5.5 assist line in five of his last ten games, and the path to doing it again in Game 2 against the Spurs is firmly in place.

A key factor is lineup synergy. Playing alongside high-efficiency scorers and floor spacers means Holiday doesn’t need high volume to rack up assists, just clean looks created within the flow of the offense. If those shots are falling at a reasonable rate, 6+ assists becomes a very reachable threshold.

🔥 Bet holiday Now at bet365!

Scoot Henderson Over 1.5 3-pointers (+115)

Projection: 1.64 3-pointers

This season, opposing starting point guards have knocked down 40.4% of their 3-point attempts against the Spurs, the fifth-highest mark allowed in the league, setting up a favorable matchup for Scoot Henderson, who has cashed the Over in seven of his last 10 games on a 1.5 made threes line.

🔥 Bet henderson Now at bet365!


Spurs Game 2 computer picks

Victor Wembanyama Under 28.5 points (-120)

Projection: 28.4 points

The Spurs are likely to see fewer scoring opportunities tonight, as they match up with the Trail Blazers, who have played at the sixth-slowest pace in the league over their last five games. That slower tempo could make it tougher for Victor Wembanyama to clear his points prop in Game 2.

🔥 Bet wembanyama Now at bet365!

Victor Wembanyama Over 11.5 rebounds (-115)

Projection: 12.01 rebounds

The Spurs have been one of the stronger offensive rebounding teams in the league, ranking sixth over their last 15 games, and Wemby has been a major contributor on the glass, clearing the Over in seven of his last 10 games on an 11.5 rebound line.

🔥 Bet wembanyama Now at bet365!

De'Aaron Fox Over 5.5 assists (-120)

Projection: 6.4 assists

De'Aaron Fox has gone over the 5.5 assist mark in five of his last 10 games, and there’s a strong case for that trend continuing against the Trail Blazers.

Fox’s playmaking often scales with defensive attention, and Portland tends to collapse on dribble penetration, especially against high-speed guards. That’s where Fox thrives.

His ability to get downhill forces help defenders to rotate, creating clean passing lanes to shooters and bigs in favorable positions. Even if he’s aggressive as a scorer early, that pressure typically opens up assist opportunities as the game progresses.

🔥 Bet fox Now at bet365!

How to watch Trail Blazers vs Spurs Game 2

Location Frost Bank Center, San Antonio, TX
Date Tuesday, April 21, 2026
Tip-off 8:00 p.m. ET
TV NBC/Peacock

Not intended for use in MA.
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Aisha Quiñones - Covers
Betting Analyst

Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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