The Los Angeles Lakers will have a key player back in the lineup as they continue their East Coast road trip against the Philadelphia 76ers on Sunday night.
With Luka Doncic back in the lineup, I like Los Angeles to cover the spread in my Lakes vs. 76ers predictions.
Keep reading to take a closer look at tonight’s matchup in my free NBA picks for Sunday, December 7.
Lakers vs 76ers prediction
Lakers vs 76ers best bet: Lakers -4 (-105)
The Los Angeles Lakers have lost two of their last three games, but two of those games came without superstar Luka Doncic, who was off for the birth of his daughter, Olivia.
Obviously, this is a different team with Doncic on the floor. The 26-year-old is leading the NBA with 35.3 ppg, while also averaging 8.9 rebounds and 8.9 assists per game.
Having him back immediately makes every matchup more difficult for the Philadelphia 76ers while lengthening the Los Angeles rotation, especially with Marcus Smart out with a muscle strain and LeBron James remaining questionable.
But it’s not just the return of Luka that should have Lakers fans confident going into tonight’s game. Los Angeles’ 126-105 loss to the Boston Celtics on Friday came in the second game of a back-to-back, and a day off should have the Lakers in better shape tonight.
The 76ers have played solid basketball this year – they’re riding a three-game winning streak right now – but this Lakers team is special with Doncic back in the lineup.
Without a healthy Joel Embiid (questionable with a left knee injury), Philadelphia will struggle to keep up with the scoring punch of Doncic and Austin Reaves (29.3 ppg). I’m taking the Lakers to cover.
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Lakers vs 76ers same-game parlay
The biggest advantage the Lakers have tonight is the return of a healthy and rested Luka Doncic, and that’s what I’m targeting for my SGP in this game.
Doncic is averaging 55.1 PRA this year, making him a good bet to hit his Over tonight, which should also help lift the total to the Over, something the Lakers have hit in six straight games.
Lakers vs 76ers SGP
- Lakers -4.5
- Over 233.5
- Luka Doncic Over 49.5 points + rebounds + assists
Our "from downtown" SGP: Doncic messes around
Already with one triple-double on the year, well-rested, and averaging nearly nine rebounds and assists per game, I’m taking a flyer on Doncic to get another triple double tonight as part of a longshot SGP.
Lakers vs 76ers SGP
- Lakers -4.5
- Over 233.5
- Luka Doncic Over 49.5 points + rebounds + assists
- Luka Doncic to record a triple-double
Lakers vs 76ers odds
- Spread: Los Angeles -4 (-105) | Philadelphia +4 (-115)
- Moneyline: Los Angeles -165 | Philadelphia +140
- Over/Under: Over 233 (-110) | Under 233 (-110)
Lakers vs 76ers betting trend to know
The Lakers are 14-8 ATS overall this season. Find more NBA betting trends for Lakers vs. 76ers.
How to watch Lakers vs 76ers
| Location | Xfinity Mobile Arena, Philadelphia, PA |
| Date | Sunday, December 7, 2025 |
| Tip-off | 7:30 p.m. ET |
| TV | Spectrum SportsNet, NBC Sports Philadelphia |
Lakers vs 76ers latest injuries
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