The Philadelphia 76ers welcome the Chicago Bulls to Xfinity Mobile Arena tonight as they look to bounce back from a tough loss to the Oklahoma City Thunder.
My Bulls vs. 76ers predictions are eyeing Philly to get back in the win column on its home court.
Read more in my NBA picks for Wednesday, March 25.
Bulls vs 76ers prediction
Bulls vs 76ers best bet: 76ers -6 (-110)
The Philadelphia 76ers are staying afloat despite being bitten by the injury bug. They’re in seventh place in the Eastern Conference with a 39-33 record, and will likely be in the Play-In Tournament.
Tyrese Maxey remains out, while Joel Embiid is a game-time decision due to an oblique injury. Paul George is also on track to return from a 25-game suspension.
Nonetheless, Philadelphia has still found ways to win without its stars. It's won four of its last six games, and Nick Nurse’s squad covered tonight’s spread in three of those. While the Sixers have lost both meetings with the Chicago Bulls this season, they were on the road and came from a time when Chicago was competitive.
The Sixers are 20-17 at home, and the Bulls are 11 games below .500 on the road. Philly has also covered the spread in two of its last three games at Xfinity Mobile Arena. Meanwhile, Chicago has lost three of their last four on the road, failing to cover the spread in each of those defeats.
Philadelphia will finally end its losing skid against the Bulls and strengthen its case for the Play-In. The return of both Embiid and PG will be huge.
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Bulls vs 76ers same-game parlay
VJ Edgecombe has been a brilliant piece for the Sixers in 2025-26, averaging 16 points per game. He’s had even more of a run lately due to the absences, and the youngster has cashed the Over in three straight. Edgecombe just dropped 35 points on the Thunder.
He had 38 points last Thursday against the Kings, too, and he’s hit the Over in points in two of his last four at home.
He’s also cashed the Over in triples in two of his last three, and Edgecombe just went 7-for-15 from deep in the loss to Oklahoma City.
Bulls vs 76ers SGP
- 76ers -6
- VJ Edgecombe Over 20.5 points
- VJ Edgecombe Over 2.5 made threes
Our "from downtown" SGP: By George, he's still got it!
Nurse said George won’t require a ramp-up period, which means he should play decent minutes tonight. He’s averaging 2.3 makes from deep for a 38% clip this season at home, and in one meeting against the Bulls, PG was 4-for-9 from 3-point territory.
Dominick Barlow is averaging 8.0 PPG for the Sixers and 7.4 at home. He’s averaging 7.5 in March so far, and the big man has cashed the Over in points in five of his last eight appearances.
Bulls vs 76ers SGP
- VJ Edgecombe Over 20.5 points
- VJ Edgecombe Over 2.5 made threes
- Paul George Over 2.5 made threes
- Dominick Barlow Over 7.5 points
Bulls vs 76ers odds
- Spread: Bulls +6 (-110) | 76ers -6 (-110)
- Moneyline: Bulls +195 | 76ers -240
- Over/Under: Over 239.5 (-110) | Under 239.5 (-110)
Bulls vs 76ers betting trend to know
The 76ers have covered the 4Q Spread in 10 of their last 12 games (+7.65 Units / 55% ROI). Find more NBA betting trends for Bulls vs. 76ers.
How to watch Bulls vs 76ers
| Location | Xfinity Mobile Arena, Philadelphia, PA |
| Date | Wednesday, March 25, 2026 |
| Tip-off | 7:00 p.m. ET |
| TV | CHSN, NBCSP |
Bulls vs 76ers latest injuries
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