The New York Knicks have won seven straight games, and they’ll look to extend their win streak when the Philadelphia 76ers come to town.
Tyrese Maxey’s recent two-game absence has caused his scoring line to slip, and my 76ers vs. Knicks predictions expect the elite offensive option to have a productive night, albeit in a loss.
Here are my best NBA picks for this Atlantic Division matchup on Friday, December 19.
76ers vs Knicks prediction
76ers vs Knicks best bet: Tyrese Maxey Over 26.5 points (-130)
Averaging a career-best 31.5 points per game, Tyrese Maxey is one of the Association’s best scorers. He’s missed the Philadelphia 76ers' last two games with an illness, but Maxey will be back in action tonight.
Maxey’s scoring line has taken a hit for Friday’s showdown, and I’m ready to take advantage. He’s scored at least 27 points in 16 of 23 games. He’s averaging 31 points at home compared to 32.2 on the road, and he’s hit the Over on this line in six of nine away games.
Before missing back-to-back games, Maxey scored at least 27 points in four of five games, and I expect him to be at his best as he and the Sixers try to snap the New York Knicks' league-leading, six-game win streak.
This is a great opportunity to take advantage of a mispriced line.
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76ers vs Knicks same-game parlay
New York has won seven straight games and covered in six of them. The Knicks won the NBA Cup with a convincing win over the San Antonio Spurs, but it took a Jalen Brunson go-ahead three-pointer to take down the Indiana Pacers on Thursday night.
New York is 18-9 ATS this season, and I expect them to cover a small spread as the home favorite.
Both teams rank in the top-10 in fewest points allowed, so I'm targeting the Under on tonight's point total. The Knicks have hit the Over in four of their last seven, while the 76ers have hit the Under in five of their previous six.
76ers vs Knicks SGP
- Tyrese Maxey Over 26.5 points
- Knicks -5
- Under 229
Our "from downtown" SGP: Brunson Leads Knicks!
Jalen Brunson has scored at least 30 points in 13 of 24 games this season, including four of his last five. He's reached that mark in seven of 13 home games, and he should continue rolling tonight as he duels with Maxey at MSG.
76ers vs Knicks SGP
- Tyrese Maxey Over 26.5 points
- Knicks -5
- Under 229
- Jalen Brunson Over 29.5 points
76ers vs Knicks odds
- Spread: 76ers +5 (-110) | Knicks -5 (-110)
- Moneyline: 76ers +170 | Knicks -205
- Over/Under: Over 229 (-110) | Under 229 (-110)
76ers vs Knicks betting trend to know
The New York Knicks have covered the Spread in 25 of their last 33 games at Madison Square Garden(+16.20 Units / 45% ROI). Find more NBA betting trends for 76ers vs. Knicks.
How to watch 76ers vs Knicks
| Location | Madison Square Garden, New York, NY |
| Date | Friday, December 19, 2025 |
| Tip-off | 7:00 p.m. ET |
| TV | Prime Video |
76ers vs Knicks latest injuries
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