MLB Spring Training Picks and Predictions for March 22: Woo, Yeah!

Jason Wilson - Betting Analyst at Covers.com
Jason Wilson • Betting Analyst 19+ years betting experience
Updated: Mar 22, 2026 , 12:59 PM ET • 4 min read

Bryan Woo has outpitched his ERA this spring, limiting walks and keeping the ball in the yard. He'll overmatch a White Sox lineup as the Mariners win tonight's spring training game.

Bryan Woo Seattle Mariners MLB
Photo By - Reuters Connect. Seattle Mariners pitcher Bryan Woo against the Kansas City Royals during a spring training game at Surprise Stadium.

Spring training is starting to wind down, but there are still some key matchups to pinpoint with our MLB picks.

I'm looking at the Under on a lofty total and a pair of moneylines, including the Seattle Mariners over the Chicago White Sox, on Sunday, March 22.

Spring Training predictions for March 22

Pick Odds
Reds/Guardians Under 11 -110
Athletics A's moneyline -130
Mariners Mariners moneyline -155
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Pick #1: Reds vs. Guardians - Under 11

Opening Day is less than a week away, so starters aren't aiming for one or two innings and calling it a day. They're looking to replicate the workload of an early-season start.

Cincinnati Reds left-hander Nick Lodolo and Cleveland Guardians right-hander Gavin Williams are poised to be front-end starters in their respective rotations.

And while both have inflated ERAs this spring, their peripherals have been encouraging (both have posted better xFIP numbers and have generally missed bats while not issuing a lot of walks).

Also, Cleveland has four left-handers in its starting lineup today, which seems at least somewhat counterintuitive against a top-flight southpaw like Lodolo. Runs will be at a premium here.

Pick #2: A's moneyline

It's tempting to take the Colorado Rockies at plus money, but with Michael Lorenzen and his 14.29 spring ERA on the mound, the A's could get into the bullpen early. It's a small sample size for the right-hander, but it hasn't been pretty, and the matchup couldn't be worse.

Even though leadoff man Nick Kurtz hasn't fully awoken yet, hitters 2-4, Shea Langeliers, Tyler Soderstrom, and Brent Rooker, each have an OPS north of 1.000 this spring. Lawrence Butler's .958 isn't far off, either.

A's lefty Jeffrey Springs has been uneven, thanks largely to a high walk rate, but he'll have better luck at keeping the opposing bats at bay.

I'd also consider Over 12.5 (-110), but that is a lofty number, especially if Springs pitches to his potential.

Pick #3: Mariners moneyline

Seattle Mariners right-hander Bryan Woo has pitched better than his 4.70 ERA (in 7 2/3 innings) suggests. He hasn't surrendered a home run and has only issued one walk.

Seattle also has the edge in any potential lineup comparison, with Cal Raleigh, Julio Rodriguez, and Randy Arozarena all back from the World Baseball Classic. 

The Chicago White Sox will be better this season than in recent years, but they're still in a full-on rebuild, and Shane Smith has been crushed this spring, so I'll pay a bit of juice to get the better pick here.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Jason Wilson Covers.com
Betting Analyst

Jason Wilson is an experienced journalist who has worked in a variety of roles within the industry for the past 18 years. Working at community newspapers in New Brunswick, Jason wore many hats as a reporter, editor, and photographer, covering everything from sports to courts to municipal politics. After shifting gears and working as an educator for a few years in the 2010s, Jason returned to full-time work in media as an MLB news editor for six years at theScore in Toronto before joining Covers in late 2021.

He has honed his editorial acumen over his years in the industry, showcasing flexibility, patience, and a strong work ethic. While he was relatively new to sports betting upon joining Covers, Jason has taken the plunge with gusto to learn the ins and outs of the industry, both as a method to improve professionally and to add an extra angle to his sports fandom.

In addition to sports, Jason is an avid film nut and former movie critic who monitors the Academy Awards betting odds for Covers. Jason holds a Bachelor of Arts in journalism degree and a Bachelor of Education degree from St. Thomas University.

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