It’s an interleague tilt at Petco Park with the Kansas City Royals visiting the San Diego Padres tonight.
San Diego veteran Nick Pivetta has been extremely sharp at home, while Kansas City right-hander Michael Lorenzen has struggled on the highway.
My Royals vs. Padres predictions expect the home team to prevail in front of the Friar faithful.
Read more in my MLB picks for Friday, June 20.
Royals vs Padres prediction
My Royals vs Padres best bet: Padres moneyline (-150 at Pinnacle)
There has been a move to the Kansas City Royals side of this moneyline, and I just don’t agree with it.
The San Diego Padres are 21-12 at home, and Royals righty Michael Lorenzen sports a suspect 4.91 ERA and 1.36 WHIP, including respective 5.94 and 1.43 marks on the road.
Additionally, Kansas City ranks 27th in wOBA and 28th in ISO against right-handed pitching. The Friars have veteran Nick Pivetta slated to start, and he’s been sharp at home with a 2.40 ERA and 0.85 WHIP.
Take San Diego to prevail at Petco tonight.
Royals vs Padres same-game parlay (SGP)
Padres moneyline
Nick Pivetta Under 2.5 earned runs
Bobby Witt Jr. Over 1.5 hits + runs + RBI
Pivetta's strikeout numbers also skyrocket at home, boosting a 10.23 K/9 and 30.1 K% compared to 9.71 and 25.3% marks on the highway.
The 32-year-old righty has also held opposing lineups to two earned runs or fewer in six of eight starts at Petco.
Royals star Bobby Witt Jr. has a splash of statistical correction ahead against right-handed pitchers and is heating up during a 7-for-15 stretch at the dish with six runs and a pair of RBI.
Witt crushed righties the past two years with a .381 wOBA, .246 ISO, and .907 OPS, so I expect better times ahead given his respective .347, .212, and .816 marks in 2025.
Royals vs Padres odds
Royals vs Padres live odds
Royals vs Padres opening odds
- Moneyline: Kansas City +160 | San Diego -190
- Run line: Kansas City +1.5 (-140) | San Diego -1.5 (+120)
- Over/Under: Over 7.5 (-110) | Under 7.5 (-110)
Royals vs Padres trend
San Diego has hit the run line in 19 of its last 32 home games (+8.45 Units / 23% ROI). Find more MLB betting trends for Royals vs. Padres.
How to watch Royals vs Padres and game info
| Location | PETCO Park, San Diego, CA |
| Date | Friday, 6-20-2025 |
| First pitch | 9:40 p.m. ET |
| TV | Apple TV+ |
| Royals starting pitcher | Michael Lorenzen (4-7, 4.91 ERA) |
| Padres starting pitcher | Nick Pivetta (7-2, 3.40 ERA) |
Royals vs Padres latest injuries
Royals vs Padres weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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