Red Sox vs Cubs Prediction, Picks & Odds — Saturday, July 19

Our expert MLB predictions offer plenty of reasons to fade Cubs starter Shota Imanaga tonight when he meets the Boston Red Sox.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Jul 19, 2025 • 09:59 ET • 4 min read

MLB

Match starts: 4 hrs
CHC
68 %
BOS
32 %
EXPERT PICK - PROP
Shota Imanaga u17.5  Outs Recorded (+105) Shota Imanaga u17.5 Outs Recorded (+105)
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Shota Imanaga of the Chicago Cubs
Photo By - Imagn Images. Shota Imanaga of the Chicago Cubs.

The Boston Red Sox and Chicago Cubs clash at Wrigley Field on Saturday night. Chicago will send ace Shota Imanaga to the hill tonight but my Red Sox vs. Cubs predictions are fading him.

See why with my best free MLB picks for this interleague showdown on July 19.

Red Sox vs Cubs prediction

My Red Sox vs Cubs best bet: Shota Imanaga Under 17.5 outs (+105 at bet365)

Chicago Cubs southpaw Shota Imanaga has pitched to a sparkling 2.65 ERA with a 0.93 WHIP through 12 starts. 

That said, there are several reasons to fade Imanaga here. The first is that the Boston Red Sox are red-hot at the plate, ranking second in the majors in OPS (.818) and runs per game (5.83) over the last 30 days.

Boston also excels against lefties, batting an MLB-high .272 with an OPS of .790. 

Another factor to consider is that Imanaga's underlying metrics are poor. His expected ERA is at 3.81, and he's in the bottom 25th percentile in average exit velocity and barrel rate.

He's also in the bottom 3% in ground ball rate, which could lead to trouble with the wind blowing out at Wrigley on a hot and humid night.

Keep in mind that Imanaga has struggled at home, pitching to a 4.61 ERA, and despite how productive he's been this year, he's logged fewer than 17.5 outs in eight of 12 starts overall. 

This is a five-star play according to THE BAT X, which is projecting 15.2 outs for Imanaga today.

Red Sox vs Cubs same-game parlay (SGP)

Imanaga Under 5.5 strikeouts

Bello Under 4.5 strikeouts

Story 2+ total bases

We can't play the Under 17.5 outs for Imanaga in an SGP, so let's find another way to fade him. He's in the bottom 25th percentile in strikeout rate and has finished with fewer than 5.5 strikeouts in nine of 12 starts.

I'm also fading Red Sox starter Brayan Bello on his strikeouts total. Bello is in the bottom 25th percentile in strikeout rate, chase rate, and whiff rate. He has struck out fewer than 4.5 batters in nine of 15 starts this year.

There's a solid chance Bello gets chased early by the Cubs, who lead the majors in scoring. Even if he has a decent workload, he'll have a tough time generating punchouts against a lineup that ranks fourth in strikeout rate.

Meanwhile, Boston's Trevor Story is red-hot and will have the platoon advantage against Imanaga. The two-time Silver Slugger was ice-cold at the beginning of the season but has turned things around. He has slugged .541 since the start of June and is slashing .377/.415/.672 over the last 16 games. 

Red Sox vs Cubs odds

Red Sox vs Cubs live odds

Red Sox vs Cubs opening odds

  • Moneyline: Boston +125 | Chicago -150
  • Run line: Boston +1.5 (-160) | Chicago -1.5 (+135)
  • Over/Under: Over 9.0 (-105) | Under 9.0 (-115)

Red Sox vs Cubs trend

The Red Sox have hit the First Five Innings (F5) Team Total Over in 22 of their last 34 away games (+8.05 Units / 19% ROI). Find more MLB betting trends for Red Sox vs. Cubs.

How to watch Red Sox vs Cubs and game info

Location Wrigley Field, Chicago, IL
Date Saturday, 7-19-2025
First pitch 7:15 p.m. ET
TV FOX
Red Sox starting pitcher Brayan Bello
(6-3, 3.14 ERA)
Cubs starting pitcher Shota Imanaga
(6-3, 2.65 ERA)

Red Sox vs Cubs latest injuries

Red Sox vs Cubs weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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