Giants vs Dodgers Prediction, Picks & Odds — Friday, September 19

Parker's prediction: Ohtani stays hot at the dish.

Chris Faria - Contributor at Covers.com
Chris Faria • Betting Analyst
Sep 19, 2025 • 12:14 ET • 4 min read

MLB

Match starts: 7 hrs
LAD
69 %
SF
31 %
EXPERT PICK - PROP
Shohei Ohtani o1.5  Total Bases (-110) Shohei Ohtani o1.5 Total Bases (-110)
Read Analysis
Shohei Ohtani Los Angeles Dodgers MLB
Photo By - Imagn Images. Los Angeles Dodgers designated hitter Shohei Ohtani (17).

Shohei Ohtani has been feasting at the plate this month, and I expect that trend to continue when the Los Angeles Dodgers host the San Francisco Giants tonight.

I’ll break down why I think Ohtani eclipses 1.5 total bases in my Giants vs. Dodgers predictions for Friday, September 19.

Read more in my latest MLB picks, with first pitch set for 10:10 p.m. ET on Apple TV+.

Giants vs Dodgers prediction

Giants vs Dodgers best bet: Shohei Ohtani Over 1.5 total bases (-110)

If Shohei Ohtani wasn’t already a shoo-in for his second straight National League MVP award, he certainly is now.

The Los Angeles Dodgers superstar is batting .344 in September while boasting a team-leading 46 total bases, and he’s been even hotter this past week.

Ohtani recorded two doubles in last night’s series opener and has now gone Over 1.5 total bases in four straight games. He’s also gone yard three times over that span.

San Francisco Giants starter Robbie Ray was initially having a decent season, but the wheels have fallen off over the last few weeks. The left-hander owns a massive 7.83 ERA over his last five starts, having surrendered 4+ earned runs in three of his last four appearances.

Giants vs Dodgers same-game parlay (SGP)

Mookie Betts is just 1-for-11 over his last three games, but the Dodgers outfielder was on a heater earlier this month. His 19 RBI in September are the most in the majors, and he’ll get back on track against a struggling Ray.

The Dodgers are 5-1 in their last six meetings against the Giants and should make relatively easy work of a San Fran team that looks poised to miss the postseason for the fourth straight year.

Giants vs Dodgers SGP

  • Dodgers moneyline
  • Mookie Betts Over 0.5 RBI
  • Shohei Ohtani Over 1.5 total bases

Giants vs Dodgers odds

  • Moneyline: San Francisco +135 | Los Angeles -160
  • Run line: San Francisco +1.5 (-170) | Los Angeles -1.5 (+140)
  • Over/Under: Over 8.5 (-105) | Under 8.5 (-115)

Giants vs Dodgers trend

Los Angeles is 11-2 in its last 13 meetings against the Giants at home. Find more MLB betting trends for Giants vs. Dodgers.

How to watch Giants vs Dodgers and game info

Location Dodger Stadium, Los Angeles, CA
Date Friday, September 19, 2025
First pitch 10:10 p.m. ET
TV Apple TV+
Giants starting pitcher Robbie Ray
(11-7, 3.50 ERA)
Dodgers starting pitcher Clayton Kershaw
(10-2, 3.53 ERA)

Giants vs Dodgers latest injuries

Giants vs Dodgers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Chris Faria - Covers
Betting Analyst

After writing a few pieces for the Varsity newspaper during his time at the University of Toronto, Chris Faria's career in sports truly began in 2019 when he attended the sports journalism program at Centennial College. Since then, he’s covered virtually every sport under the sun, having written for several different outlets including Covers and the Canadian Olympic Committee. A lifelong hockey fan and player, Chris currently works full-time for the National Hockey League.

Outside of hockey, he’s also an avid poker player and mixed martial arts fan, which is coincidentally his favorite sport to bet on – usually in the form of a parlay on bet365. The main lesson he’s learned from years of betting is bankroll management: "Never bet more than you’re comfortable losing and never chase your losses."

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo