Dodgers vs Cardinals Prediction, Picks & Odds for Today’s MLB Game

The Los Angeles Dodgers are in a tough spot pitching-wise, as they send Justin Wrobleski to the bump on Friday. As JD Yonke explains, he'll be in tough to keep Willson Contreras off the bases.

JD Yonke - Contributor at Covers.com
JD Yonke • Contributor
Jun 6, 2025 • 10:13 ET • 4 min read
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This article contains predictions for an old game!

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St. Louis Cardinals first baseman Willson Contreras (40) reacts after hitting a two run double.
Photo By - Imagn Images. St. Louis Cardinals first baseman Willson Contreras (40) reacts after hitting a two run double.

The Los Angeles Dodgers (38-25) and St. Louis Cardinals (34-28) begin a three-game weekend series on Friday night at Busch Stadium. 

For today’s best bet, I’m eyeing Willson Contreras in the player prop market with my Dodgers vs. Cardinals predictions and free MLB picks for Friday, June 6.

Dodgers vs Cardinals prediction

My Dodgers vs Cardinals best bet: Willson Contreras Over 1.5 Total Bases (+130 at bet365)

Due to a regrettable number of starting pitcher injuries, the Los Angeles Dodgers will throw out 24-year-old Justin Wrobleski for Friday’s series opener. 

Across 45 ⅓ IP in the Big Leagues, the left-hander has accrued a 6.15 ERA and 6.13 FIP. Which, yikes.

He wasn’t showing a tremendous amount of progression at AAA this season, either, with a 5.09 ERA and 5.59 FIP. 

Pitching on the road at Busch Stadium may be a challenge for the young hurler, as evidenced by his 8.10 ERA across 30 IP in away games in his MLB career. 

Wrobleski hasn’t figured out how to routinely retire right-handed batters, sporting a 1.43 WHIP and 6.54 FIP against them with a 16% K rate and 10.7% walk rate. 

One St. Louis Cardinals batter who should be ready to capitalize is Willson Contreras

He’s hit lefties well this season (135 wRC+) and is in fine form, going 7-for-20 with seven RBI and four extra base hits in his last five games. 

Wrobleski typically attacks right-handers with four-seamers, curveballs, and cutters. Contreras has favorable results against all three pitch types (142 wRC+ against four-seamers, 126 wRC+ against curves, 154 wRC+ against cutters). 

Wrobleski, a former Oklahoma State product, probably doesn’t have the longest leash in this game, but he’s been operating as a starter in AAA and likely pitches through the lineup a few times. 

Once things make it to the bullpen, Contreras still has a favorable outlook against an LA arm barn that has a 4.44 ERA and 4.77 xFIP since May 15. 

The first baseman ranks in the 96th percentile in bat speed and has good results overall this season with a .373 xwOBA, .286 xBA, and .508 xSLG. I’ll bet on him recording 2+ total bases.

Dodgers vs Cardinals same-game parlay (SGP)

Cardinals moneyline

Ivan Herrera 2+ H/R/R

Wilson Contreras 2+ total bases

St. Louis has to like its chances on Friday with Sonny Gray on the mound going against a 24-year-old spot starter. The Cardinals are 20-10 at Busch Stadium while the Dodgers are a mediocre 15-14 on the road. 

Ivan Herrera is another right-handed batter with a favorable matchup, going 11-for-42 (.344) with a 237 wRC+ in a small sample size against left-handed pitching. 

The young backstop is making waves with a .397 xwOBA, a .297 xBA, and a .543 xSLG. He’s in fine form with at least one hit in four consecutive games, and he has a .362/.436/.660 slash line in 14 home games.

Dodgers vs Cardinals odds

Dodgers vs Cardinals live odds

Dodgers vs Cardinals opening odds

  • Moneyline: Los Angeles -105 | St. Louis -105
  • Run line: Los Angeles -1.5 (+155) | St. Louis +1.5 (-185)
  • Over/Under: Over 8.5 | Under 8.5

Dodgers vs Cardinals trend

The Cardinals have hit the moneyline in 20 of their last 30 home games. Find more MLB betting trends for Dodgers vs. Cardinals.

How to watch Dodgers vs Cardinals and game info

Location Busch Stadium, St. Louis, MO
Date Friday, 6-6-2025
First pitch 8:15 p.m. ET
TV SNLA, FDSNMW
Dodgers starting pitcher Justin Wrobleski
(1-1, 8.00 ERA)
Cardinals starting pitcher Sonny Gray
(6-1, 3.65 ERA)

Dodgers vs Cardinals latest injuries

Dodgers vs Cardinals weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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JD Yonke
Contributor

JD is a diehard college football fan with five years of experience writing betting and fantasy content for publications such as SportsGrid, Fantasy Points, Fantrax, and Devy Watch. An avid reader, he uses his inclination to look at things with an exhausting and in-depth, analytic viewpoint combined with a love for statistics and metrics to form a well-rounded handicapping approach.

e's an integral member of the niche (but growing!) college fantasy football community, twice traveling to Canton, OH for the Fantasy Football Expo as a member of the CFF King's Classic drafting squad. His specialization in college football DFS and prop betting taught him that there are exploitable markets to be found and that narrowing your focus is integral to being a profitable bettor.

A lifelong Californian who grew up playing baseball, basketball, football, and lacrosse, he's glad to share a passionate love for sports with this wonderful community.

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