The Chicago Cubs will look to make up ground in the NL Central race as they host the Milwaukee Brewers for the second game of a doubleheader on Tuesday night.
Chicago earned a much-needed win in Game 1 today, but I’m picking Milwaukee to even up the score in my Brewers vs. Cubs predictions below.
Let’s take a closer look at tonight’s matchup in my free MLB picks for Tuesday, August 19.
Brewers vs Cubs prediction
Brewers vs Cubs best bet: Brewers moneyline (-115)
Brandon Woodruff gets the start for the Milwaukee Brewers tonight, and he has been outstanding since finally making his return from a right shoulder surgery that cost him all of last year. While his velocity is down a bit, Woodruff has been incredibly effective in seven starts, going 4-0 with a 2.06 ERA and a sterling 0.737 WHIP. In fact, Woodruff hasn’t allowed more than two runs in any of his starts yet this year.
The Chicago Cubs may have a little less confidence in Jameson Taillon. The veteran is 7-6 with a 4.44 ERA on the year, but has been allowing far too many home runs to be as effective as he’d like to be. Opponents have hit 22 longballs in 95.1 innings against Taillon.
He’s also been out since June 29 with a right calf injury, so it’s uncertain how long he’ll be able to go tonight.
So it will be up to a returning Taillon and a bullpen that’s already thrown nearly four innings today to shut down the Brewers, who average a league-leading 5.20 runs per game.
Brewers vs Cubs same-game parlay (SGP)
There’s an excellent pitching matchup on tap for the nightcap, but these teams are each in the top five in the majors in runs per game, so I have to take the Over on a dismal total of 6.5 runs.
Brandon Woodruff has gone for 6+ strikeouts in five of his seven starts this season, so I’ll take that Over as well. Let’s also throw in a bet on William Contreras to get at least one hit, something he has done in nine of his last 10 games.
Brewers vs Cubs odds
- Moneyline: Milwaukee -110 | Chicago -101
- Run line: Milwaukee -1.5 (+155) | Chicago +1.5 (-190)
- Over/Under: Over 7 | Under 7
Brewers vs Cubs trend
The Brewers are 7-0 in games started by Brandon Woodruff this season. Find more MLB betting trends for Brewers vs. Cubs.
How to watch Brewers vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Tuesday, August 19, 2025 |
| First pitch | 8:05 p.m. ET |
| TV | FDSNWI, MARQ |
| Brewers starting pitcher | Brandon Woodruff (4-0, 2.06 ERA) |
| Cubs starting pitcher | Jameson Taillon (7-6, 4.44 ERA) |
Brewers vs Cubs latest injuries
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Odds are correct at the time of publishing and are subject to change.
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