Astros vs Braves Prediction, Picks & Odds — Friday, September 12

Hurston Waldrep has been dealing, and our expert MLB predictions expect Waldrep to continue his hot hand against the Astros.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Sep 12, 2025 • 08:45 ET • 4 min read

MLB

Match starts: 7 hrs
ATL
67 %
HOU
33 %
EXPERT PICK - MONEYLINE
Atlanta +110 Atlanta +110
Read Analysis
Hurston Waldrep of the Atlanta Braves
Photo By - Jim Rassol-Imagn Images

The Houston Astros head down to Georgia tonight to begin a three-game series with the Atlanta Braves at Truist Park.

Hurtson Waldrep has been dominant on the hill, and my Astros vs. Braves predictions will explain why I believe he’ll lead Atlanta to a victory.

Read more in my MLB picks for Friday, September 12.

Astros vs Braves prediction

Astros vs Braves best bet: Atlanta Braves moneyline (+110)

The Atlanta Braves just dropped two of three to the Chicago Cubs, but there’s reason to believe they will bounce back in the series opener versus the Houston Astros. Braves starter Hurston Waldrep has posted a 1.33 ERA through seven starts, with opponents hitting just .191.

The youngster has been a bright spot in Atlanta's otherwise poor season. He’s compiled a 1.50 ERA at home across three outings, giving up just three earned runs in 18 innings of work. The Braves have also won three straight against the Astros.

Houston just got shut out 6-0 by the Toronto Blue Jays on Thursday, with Kevin Gausman throwing a complete game. The Astros' offense isn’t exactly coming in hot, and Waldrep should benefit and help his team grind out a victory.

Astros vs Braves same-game parlay (SGP)

As previously mentioned, Waldrep hasn’t given up a whole lot of runs since coming up to the Majors. While he had a brief cup of coffee last year, he’s been handed a bigger role in 2025 due to Atlanta’s injuries.

Waldrep has surrendered Under 2.5 earned runs in every single start since getting called up. He allowed just two earned runs last time out against the Seattle Mariners.

Yordan Alvarez finished 0-for-4 on Thursday, but he had cashed the Over in total bases in three of his four previous games. The Cuban put together a pair of multi-hit games in the first two games of the Blue Jays series. He’s batting .272 against right-handed pitchers.

Astros vs Braves SGP

  • Atlanta Braves moneyline (+110)
  • Hurstron Waldrep Under 2.5 earned runs (-125)
  • Yordan Alvarez Over 1.5 total bases (-105)

Astros vs Braves odds

  • Moneyline: Houston (-130) | Atlanta (+110)
  • Run line: Houston -2.5 (+200) | Atlanta +2.5 (-275)
  • Over/Under: Over 8 (-125) | Under 8 (-102)

Astros vs Braves trend

The Atlanta Braves have hit the Moneyline in 18 of their last 33 games (+2.75 Units / 7% ROI). Find more MLB betting trends for Astros vs. Braves.

How to watch Astros vs Braves and game info

Location Truist Park, Atlanta, GA
Date Friday, September 12, 2025
First pitch 7:15 p.m. ET
TV Space City HN, FDSN South
Astros starting pitcher TBD
(X-X, X.XX ERA)
Braves starting pitcher Hurston Waldrep
(4-0, 1.33 ERA)

Astros vs Braves latest injuries

Astros vs Braves weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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