The New York Mets will look to continue their strong play at Citi Field as they host the Los Angeles Angels to open their series tonight.
Kodai Senga has been outstanding when healthy this year, and I’m taking him and New York to cover the run line in my Angels vs. Mets predictions.
Let’s take a closer look at tonight’s matchup in my free MLB picks for Monday, July 21.
Angels vs Mets prediction
My Angels vs Mets best bet: Mets -1.5 (ODDS at Caesars)
The New York Mets got Kodai Senga back just before the All-Star break after he missed a month due to a hamstring strain. He immediately showed why New York needed him back so badly, throwing four shutout innings against the Kansas City Royals on July 11.
That was the latest excellent outing in a great — although injury-plagued — season for Senga. The 32-year-old is 7-3 with a 1.39 ERA in 14 starts, keeping opponents off base with a 1.13 WHIP, and an opposing .604 OPS.
The Los Angeles Angels will counter with veteran lefty Tyler Anderson, who is 2-6 with a 4.34 ERA. Anderson has been more than serviceable for Los Angeles, but he's vulnerable to the longball, having allowed 17 homers in 101 2/3 innings of work — a dangerous issue against a Mets lineup with plenty of power up top.
New York has been dominant at home, boasting a 34-16 record, and they've also had great success with Senga on the mound, winning his last five starts — four of them by at least two runs.
Caesars QuickPick: Our Angels vs Mets same-game parlay (SGP)
Mets -1.5
Under 8.5
Kodai Senga Over 5.5 strikeouts
I’m expecting Senga to come out strong for the Mets, which makes it easy to pick a couple more legs for my SGP. Let’s take the Under at 8.5 runs, as the Angels should have trouble scoring and the Mets' offense hasn’t been lighting the world on fire, either.
I’m also taking Senga to collect Over 5.5 strikeouts as he lengthens out in his return from injury.
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Angels vs Mets odds
Angels vs Mets live odds
Angels vs Mets opening odds
- Moneyline: Los Angeles +165 | New York -200
- Run line: Los Angeles +1.5 (-140) | New York -1.5 (+120)
- Over/Under: Over 8.5 (+100) | Under 8.5 (-120)
Odds courtesy of Caesars.
Angels vs Mets trend
The New York Mets have hit the moneyline in 34 of their last 50 games at home (+9.70 Units / 11% ROI). Find more MLB betting trends for Angels vs. Mets.
How to watch Angels vs Mets and game info
| Location | Citi Field, Flushing, NY |
| Date | Monday, 7-21-2025 |
| First pitch | 7:10 p.m. ET |
| TV | FDSNW, SNY |
| Angels starting pitcher | Tyler Anderson (2-6, 4.34 ERA) |
| Mets starting pitcher | Kodai Senga (7-3, 1.39 ERA) |
Angels vs Mets latest injuries
Angels vs Mets weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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