The Angels face their second opponent of the season tonight, traveling to Wrigley Field to open a three-game series against the Cubs.
The Angels surprised many with back-to-back wins to open the season. While the front-line talent may be improved in Los Angeles, the Angels showed that depth in the pitching staff is an issue, giving up 20 runs over the next two games.
My Angels vs. Cubs predictions and MLB picks are calling for the Chicago bats to hit their stride en route to a win on Monday, March 30.
Angels vs Cubs predictions
Angels vs Cubs best bet: Cubs -1.5 (+104)
The Chicago Cubs hit three homers on Sunday after plating 10 runs in Saturday’s win over Washington. Four of Chicago’s five dingers this season have been solo shots, but I think we'll see more table-setting from the Cubs’ offense tonight.
Los Angeles Angels SP Ryan Johnson is a former reliever making his first MLB start above Class A. Four of his six spring appearances were in relief, so that doesn’t indicate a long outing from him.
The Angels' bullpen has allowed 11 runs over 7 1/3 innings across the last two games.

Angels vs Cubs same-game parlay (SGP)
Two of three Cubs games this year have seen a team plate 10+ runs on their own, and the nine-run mark has been hit by a team three times in the Angels' four games.
Chicago starts Edward Cabrera, who had a career year with the Marlins last season. However, he had a 7.47 ERA and 1.532 WHIP in Spring Training while seeing his strikeout rate drop.
Ian Happ homered on Sunday and has a .978 OPS on the young season. Johnson allowed 14.7 hits and 2.5 homers per nine innings last season, so Happ could continue to tee off.
Angels vs Cubs SGP
- Cubs -1.5
- Over 9.5
- Ian Happ Over 0.5 RBI
Angels vs Cubs home run pick: Mike Trout (+240)
Is he back? He just might be.
Mike Trout hit .462 with two homers and 1.573 OPS in his first series of 2026. He’s reached base twice in three plate appearances against Cabrera, who throws a fast (87th percentile on velocity last year) but hittable four-seamer.
Trout has not missed a fastball yet this season, and both of his home runs were off of that pitch.
- Best bets: 1-3, -2.23 units
- SGPs: 0-4, -4 units
- HR picks: HR 2-5, +0.65 units
Angels vs Cubs odds
- Moneyline: Los Angeles +164 | Chicago -196
- Run line: Los Angeles +1.5 | Chicago -1.5
- Over/Under: Over 9.5 | Under 9.5
Angels vs Cubs trend
The Cubs have hit the moneyline in 42 of their last 64 games at home. Find more MLB betting trends for Angels vs. Cubs.
How to watch Angels vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Monday, March 30, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | FDSN West, Marquee |
| Angels starting pitcher | Ryan Johnson (2025: 1-1, 7.36 ERA) |
| Cubs starting pitcher | Edward Cabrera (2025: 8-7, 3.53 ERA) |
Angels vs Cubs latest injuries
Angels vs Cubs weather
Odds are correct at the time of publishing and are subject to change.
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