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Adverse Effects on the Cardiovascular System
The steroid-induced changes that may affect the development of cardiovascular disease include hyperinsulinism and altered glucose tolerance, decreased high-density lipoprotein cholesterol levels, and elevated blood pressure. These effects are variable for different individuals in various clinical situations. Triglycerides are lowered by anabolic-androgenic steroids in certain individuals and are increased in others. Histological examinations of myofibrils and mitochondria from cardiac tissue obtained from laboratory animals have shown that administration of anabolic steroids leads to pathological alterations in these structures. The cardiovascular effects of the anabolic-androgenic steroids, though potentially hazardous, need further research before any conclusions can be made.
The steroid-induced changes that may affect the development of cardiovascular disease include hyperinsulinism and altered glucose tolerance, decreased high-density lipoprotein cholesterol levels, and elevated blood pressure. These effects are variable for different individuals in various clinical situations. Triglycerides are lowered by anabolic-androgenic steroids in certain individuals and are increased in others. Histological examinations of myofibrils and mitochondria from cardiac tissue obtained from laboratory animals have shown that administration of anabolic steroids leads to pathological alterations in these structures. The cardiovascular effects of the anabolic-androgenic steroids, though potentially hazardous, need further research before any conclusions can be made.
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