Barcelona are fresh off a 6-0 win over Valencia, and they'll look to kickstart their Champions League campaign at St. James' Park against Newcastle.
My Newcastle v Barcelona predictions and free betting picks expect a high-scoring affair between the two on Thursday, September 18.
Newcastle vs Barcelona picks and predictions
My Newcastle vs Barcelona best bet: Over 3.5 goals (+110 at Sports Interaction)
Barcelona love open play and have the methods to harm any opponent on a good day. Given the amount of talent they have, it's self-explanatory why the vast majority of teams find it almost impossible to defend against them.
Barcelona scored at least three goals in three of the four matches they played in the Spanish top tier this season. All their tactical plans seem to work flawlessly, and they will not be happy with just a win in Newcastle. They're here to make a statement.
Barcelona have won 12 of their last 16 UEFA Champions League games in front of English opposition, losing on just two occasions. They scored an average of 2.1 goals per game during that run.
Newcastle have won just one of their last eight UEFA Champions League games, a 4-1 home win against Paris Saint-Germain in the 2023-24 group stage.
I'm choosing goals over the moneyline, as there is a strong indication this will be a highly eventful encounter.
Newcastle vs Barcelona same-game parlay (SGP)
Over 3.5 goals
Raphinha anytime scorer
Robert Lewandowski 2+ shots on target
Raphinha was directly involved in more goals than any other player in the UEFA Champions League last season, scoring 13 and assisting another eight. The Brazilian was only involved in the second half against Valencia at the weekend, coming on and scoring twice after the break.
Lewandowski also got himself a brace against Valencia, showing he's still capable of making things happen at this level despite turning 37 in August.
Lewandowski had 18 attempts on target last season in the Champions League from a total of 34 in 14 matches. I see him involved and ready to go again.
Newcastle vs Barcelona odds
Newcastle vs Barcelona live odds
 Newcastle |
 Barcelona |
|
|---|---|---|
| +180 | Moneyline | +125 |
| +280 | Draw | +280 |
| Over 2.5 (-217) | Total | Under 2.5 (+155) |
Odds courtesy of Sports Interaction.
Newcastle vs Barcelona opening odds
- Moneyline: Newcastle +180 | Barcelona +125
- Draw: +280
- Over/Under: Over -220 | Under +155
How to watch Newcastle vs Barcelona
| Location | St. James' Park, Newcastle, UK |
| Date | Thursday, September 18, 2025 |
| Time | 3:00 p.m. ET |
| TV | Paramount+ |
| Weather | 60F with a chance of rain. |
Newcastle vs Barcelona key injuries
Newcastle: Jacob Ramsey AM (Out), Yoane Wissa FW (Out).
Barcelona: Marc-Andre ter Stegen GK (Out), Balde LB (Questionable), Gavi CM (Out), Frenkie de Jong CM (Out), Lamine Yamal RW (Questionable)
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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