NFL Predictions: 3 Plus Money Bets to Target for Week 10

Kyren Williams faces a favorable matchup against a depleted 49ers front seven on Sunday, and the Rams running back is poised for a big performance in this NFC West showdown.

Josh Inglis - Betting Analyst at Covers.com
Josh Inglis • Betting Analyst
Nov 6, 2025 • 18:24 ET • 4 min read
Kyren Williams Los Angeles Rams NFL
Photo By - Imagn Images. Los Angeles Rams running back Kyren Williams (23).

Week 10’s plus-money board is stacked with value.

We’ve got a double-TD prop in a dream matchup, a mispriced running back whose 50+ rushing line undervalues his potential RB1 role, and a rookie tight end set up for a monster game against one of the league’s worst defenses versus the position.

It’s the kind of lineup that can turn a solid Sunday into a statement week — let’s hunt for profit in my latest NFL picks.

NFL Week 10 Predictions: Best plus money bets

Player Pick FanDuel
Rams Kyren Williams 2+ touchdowns +700
Chargers Oronde Gadsden  70+ receiving yards +188
Giants Devin Singletary 50+ rushing yards +310
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Kyren Williams 2+ touchdowns

+700 at FanDuel

This is the first time I’ve gone with a multiple-touchdown prop in this article, but Los Angeles Rams running back Kyren Williams is in a perfect spot this week.

The San Francisco 49ers have lost their entire starting defensive line, and their linebackers are banged up as well. Williams is a true workhorse who can handle 25 carries and 75% of the snaps in a game with major playoff implications.

Meanwhile, the Rams are 4.5-point favorites, Puka Nakua isn’t fully healthy, and Williams’ anytime TD price is +100 after being as short as -185 earlier this season. He’s coming off 25 carries for 114 yards and six red-zone rushes.

Feels like a double-tuddy kind of game.

Oronde Gadsden 70+ receiving yards

+188 at FanDuel

I’ll happily wait until Sunday night to hit the alt overs on Los Angeles Chargers tight end Oronde Gadsden, who draws one of the best tight-end matchups of Week 10.

The Pittsburgh Steelers are the second-most generous defense to the position, allowing 6.2 catches, 72.6 yards, and 0.8 touchdowns per game. Since breaking out in Week 6, the rookie has averaged six receptions on 6.8 targets for 94.3 yards at 15.7 per catch.

Gadsen is being targeted on 20% of his routes, trails only Trey McBride in air yards among tight ends, and leads the position with seven receptions of 20+ yards. I’m keeping it simple with the 70+ yard line — right around what Pittsburgh gives up weekly.

However, don’t rule out 100 yards at +580 in a prime indoor matchup. It was just two weeks ago in primetime that Tucker Kraft went off for seven catches, 143 yards, and two TDs vs. this Pittsburgh defense. 

Devin Singletary 50+ rushing yards

+310 at FanDuel

Devin Singletary’s rushing total is set at 29.5 yards, while Tyrone Tracy’s is at 43.5. That gap doesn’t make much sense after last week’s split workload — Singletary handled 62% of the first-down snaps and looks like the 1A in this backfield. The shorter number is worth a look up to 50+ at +310.

The New York Giants’ rushing volume against the Chicago Bears could also be higher than expected. Sunday’s forecast at Soldier Field calls for cold, wet, and windy conditions, which should push New York toward a run-heavy approach.

When it comes to game script, the Bears come into this one banged up — D’Andre Swift is hurt, and both DJ Moore and Rome Odunze were limited Thursday after missing Wednesday’s practice.

If Singletary gets 10–12 carries, 50 yards is well within reach. Only seven teams have allowed more rushing yards than Chicago this season.

Odds are correct at the time of publishing and are subject to change.
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Josh Inglis - Covers
Betting Analyst

Josh Inglis is a rising star in the sports betting content space, specializing in MLB, NHL, and NFL markets. Since joining Covers in 2019, Josh has focused his betting expertise on player props and derivative markets, finding them easier for beating the closing line compared to sides and totals. His engaging analysis and content have been showcased on major networks such as TSN, VSiN, BetMGM Network, and NBC. Josh is a prolific bettor, tracking over 2,500 bets annually and he consistently shares his results through monthly transparency reports. At Covers, he is renowned for his MLB release shows and NHL Puck Props, which are integral parts of the site's live content lineup.

Before his tenure at Covers, Josh spent a decade teaching while pursuing sports media on the side. He has also contributed to live global senior-level broadcasts for the WBSC.

Josh advocates for sports bettors to bet early, emphasizing the importance of securing better numbers by beating the public to the market. He also advises having multiple sportsbook accounts to ensure access to the best possible odds.

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