Chargers vs Dolphins Predictions, Picks & Best Bets for NFL Week 6

The Miami Dolphins' pass defense has struggled, and our expert NFL predictions expect Chargers wideout Keenan Allen to have a big day catching the football!

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Oct 10, 2025 • 11:30 ET • 4 min read

NFL

Match starts: 42 hrs
MIA
37 %
LAC
63 %
EXPERT PICK - PROP
Keenan Allen o52.5  Receiving Yards (-114) Keenan Allen o52.5 Receiving Yards (-114)
Read Analysis
Keenan Allen of the LA Chargers
Photo By - Imagn Images. Keenan Allen of the LA Chargers.

The 1-4 Miami Dolphins welcome Justin Herbert and the Los Angeles Chargers to Hard Rock Stadium.

Keenan Allen has been a consistent contributor for LA this season, and my Dolphins vs Chargers predictions are eyeing that trend to continue in Week 6.

Read more for my NFL picks for Sunday, October 12.

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Chargers vs Dolphins prediction

Chargers vs Dolphins Best bet:  Keenan Allen Over 52.5 receiving yards (-114)

The Los Angeles Chargers clearly made a great decision in bringing back Keenan Allen this offseason. The franchise legend has been balling out, reeling in 29 receptions for 289 yards and three touchdowns.

He’s also served as a veteran presence and a key weapon for Chargers quarterback Justin Herbert.

Allen has cashed the Over in receiving yards in five of his six appearances in 2025. Despite another loss last weekend to Washington, Allen still had five grabs for 58 yards. He’s averaging 10 yards per reception.

The Miami Dolphins also do not have a great secondary. They rank 16th in most passing yards allowed. This presents a clear opportunity for Allen to deliver another impressive performance.

Chargers vs Dolphins same-game parlay

With Tyreek Hill out for the rest of the season, that means Jaylen Waddle has quickly become WR1 for the struggling Dolphins. He’s more than capable of taking that title, too, despite struggles at times.

Waddle has 23 receptions for 295 yards and three touchdowns this season. Those three scores have come in the last four games as well, and he’ll be busy on Sunday. If I were going to take anyone in this Miami WR room to find the end zone, it would be Waddle.

We shift over to De’Von Achane, who has shown real promise since coming into the league. The Texas A&M product is rushing for 4.4 yards per carry this season. Although he had a brutal day in Week 5 with just 16 rushing yards, Achane did cash the Over in rushing yards in two straight games prior.

The Chargers are allowing around 120 yards per game on the ground. Achane ran for 99 yards in his last contest at Hard Rock Stadium, and he’ll be motivated to bounce back after last week’s poor performance.

Chargers vs Dolphins SGP

  • Keenan Allen Over 52.5 receiving yards
  • Jaylen Waddle anytime touchdown
  • De’Von Achane Over 56.5 rushing yards

Our big-ticket SGP: McConkey Conks Miami!

Ladd McConkey hit paydirt for the first time this season in Week 6 against Washington. He's a good bet to find the end zone Sunday against the leaky Miami secondary. 

Chargers vs Dolphins SGP

  • Keenan Allen Over 52.5 receiving yards
  • Jaylen Waddle anytime touchdown
  • De'Von Achane Over 56.5 rushing yards
  • Ladd McConkey anytime touchdown

Chargers vs Dolphins odds

  • Spread: Chargers -5.5 (-110) | Dolphins +5.5 (-110)
  • Moneyline: Chargers -250 | Dolphins +200
  • Over/Under: Over 46.5 (-105) | Under 46.5 (-115)

More NFL picks and odds from Covers


Chargers vs Dolphins trend to know

The Miami Dolphins have hit the Game Total Over in 13 of their last 20 games (+5.30 Units / 24% ROI). Find more NFL betting trends for Chargers vs. Dolphins.

How to watch Chargers vs Dolphins

Location Hard Rock Stadium, Miami, FL
Date Sunday, October 12, 2025
Kickoff 1:00 p.m. ET
TV CBS

Chargers vs Dolphins latest injuries

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Odds are correct at the time of publishing and are subject to change.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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