The LSU Tigers entered the season with sky-high expectations, but now find themselves as home underdogs against the Texas A&M Aggies this weekend.
With two SEC losses already on the books, LSU faces a daunting path — they’ll need to string together five straight wins, including three against top-15 opponents, to keep their College Football Playoff hopes alive. Otherwise, a once-promising campaign could slip away.
My Texas A&M vs. LSU predictions see those playoff dreams coming to an end in Baton Rouge this weekend.
Find out more in my college football picks for Saturday, October 25.
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Texas A&M vs LSU prediction
Texas A&M vs LSU best bet: Texas A&M -2.5 (-115)
The writing is on the wall for LSU. The Tigers went all-in on the 2025 season and are going to fall short of all their goals. This locker room may be on the verge of discord following last week's humbling loss at Vanderbilt.
Texas A&M is not who you want to face when already stumbling.
The Aggies have one of the country’s most effective rushing attacks, not only the weaker piece of the Tigers’ defense but also the piece that is more likely to allow down-to-down successes. Texas A&M should be able to run with enough success to bludgeon LSU into submission.
Meanwhile, the Tigers' offense is increasingly a worry. They haven’t scored more than 24 points against an FBS opponent this season, and the Aggies boast the toughest defense they’ve faced so far.
Texas A&M’s greatest defensive weakness is allowing short passing gains, but it limits explosive plays so effectively that there’s little reason to believe Garrett Nussmeier will break through the top of A&M’s secondary.
So the question is, can the Tigers keep the Aggies in check?
The Texas A&M physicality should eventually break through. In three of their four SEC games, the Aggies leaned on the run, finding far more success with it than they did the pass. Some of that is mere strength, in the literal sense.
Look for that to wear through the Tigers in the second half and further deflate Brian Kelly’s time in Baton Rouge.
Texas A&M vs LSU same-game parlay
Le’Veon Moss’s ankle injury has shed light on the depth of Texas A&M’s running back room.
In the first two competitive games of A&M’s season, Rueben Owens II took six total carries for 57 yards. In the last two games, he has taken 31 rushes for 120 yards and three scores. Owens should continue to find success against LSU.
Where LSU does outright struggle is bringing down opposing quarterbacks. Expect a few more Marcel Reed scrambles than usual. The Tigers will harass him, but they will struggle to sack him.
Texas A&M vs LSU SGP
- Texas A&M -2.5
- Rueben Owens Over 70.5 rushing yards
- Marcel Reed Over 31.5 rushing yards
Our deep-ball SGP: Bad Kitty
The real want here is to fade LSU’s scoring in all ways. The pace of this game alone could doom the Tigers’ points possibilities.
Worse yet, LSU averages 1.81 points per quality drive this season, the absolute worst at the FBS level this season.
Texas A&M vs LSU SGP
- Texas A&M -2.5
- Rueben Owens Over 70.5 rushing yards
- Marcel Reed Over 31.5 rushing yards
- Rueben Owens anytime touchdown
- Garrett Nussmeier Under 1.5 passing touchdowns
- LSU team total Under 23.5
Texas A&M vs LSU game predictions
Texas A&M vs LSU moneyline prediction
Given LSU’s desperation and Texas A&M’s likely inclination to grind down the Tigers over time, there could be some logic to betting on the Tigers to win the first half but the Aggies to win the game. That same-game parlay may payout as nicely as +600.
Brian Kelly cannot let Texas A&M get out to an early lead. He needs to sell out to avoid that.
Yet, an opening script is rarely enough to win a game.
Texas A&M vs LSU spread prediction
Betting on Texas A&M to win this game certainly fits with betting on the Aggies to cover this short spread.
It also warrants noting that LSU is 0-2 this season as an underdog of less than a field goal, losing both games by one possession.
Texas A&M vs LSU Over/Under prediction
Advocating for the Under 49.5 is acknowledging how wretched LSU’s offense has looked lately.
It should be repeated, the Tigers have not scored more than 24 points against an FBS opponent this season.
Texas A&M vs LSU odds
- Spread: Texas A&M -2.5 (-110) | LSU +2.5 (-110)
- Moneyline: Texas A&M -146 | LSU +124
- Over/Under: Over 49.5 (-110) | Under 49.5 (-110)
Texas A&M vs LSU trend to know
Only an Arkansas touchdown with nine seconds left last week kept Texas A&M from covering its third straight game. Find more college football betting trends for Texas A&M vs LSU.
How to watch Texas A&M vs LSU
| Location | Tiger Stadium, Baton Rouge, LA |
| Date | Saturday, October 25, 2025 |
| Kickoff | 7:30 p.m. ET |
| TV | ABC |
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Texas A&M vs LSU weather
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Odds are correct at the time of publishing and are subject to change.
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