More of these, please. Whatever version of the College Football Playoff best encourages teams like the Michigan Wolverines to go on the road to face the Oklahoma Sooners, that is the version we should all endorse.
My Michigan vs. Oklahoma predictions and college football picks see an SEC darkhorse gaining momentum in what could be a make-or-break season for its head coach. Kickoff comes at 7:30 ET on Saturday, September 6.
Michigan vs Oklahoma prediction
Michigan vs Oklahoma best bet: Oklahoma -5.5 (-105)
There is a statistical argument that offenses overly relying on the run are doomed to fail, no matter how efficient they are running the ball, with maybe half a dozen exceptions each season. In an attempt to avoid that plight, Michigan relied on an alum’s husband to land five-star quarterback Bryce Underwood.
Underwood played well in his debut last week, completing 21-of-31 passes for 251 yards (8.1 yards per attempt), but still the Wolverines relied on their ground game. And it was three times as efficient as the passing game.
If Michigan tries that again in Norman, it may simply lose a math problem. Oklahoma’s passing game should feast against a defense that was alarmingly susceptible through the air against New Mexico.
The Lobos found success on 43% of their designed dropbacks last week. That may not seem high, and it isn’t, but it is high for an offense like New Mexico’s against a defense like Michigan’s. For the quickest context, just looking at teams routed by the Big Ten last week: FAU succeeded on 27% of its passes against Maryland; Western Michigan 34% against Michigan State; Ball State 21% against Purdue. There are at least three more examples, none higher than 37%.
Sooners quarterback John Mateer should cut through such a porous defense, over and over again. Those repeated successes have too high a ceiling for the Wolverines’ running game to keep up on the scoreboard.
Michigan vs Oklahoma same-game parlay
Justice Haynes scored three touchdowns last week. More notably, he decisively led Michigan with 16 carries. If the Wolverines are in scoring range this weekend, Haynes should get the call. Thus, his anytime touchdown, even when priced at +125, should not jump this same-game parlay to +774 from +221.
Haynes's scoring will not immediately put Michigan within the spread, and that would be the only logic to so escalate this payout. Recognizing that is reason enough alone to lean into this value.
Our deep-ball SGP: TEASER
Michigan should count every quality possession as a welcome gift when facing a Brent Venables defense with a freshman quarterback. That limit alone cuts into the thought of Bryce Underwood racking up touchdown passes. Frankly, Sherrone Moore may turn to Justice Haynes on every snap inside the 10-yard line.
Michigan vs Oklahoma odds
- Spread: Michigan +5.5 | Oklahoma -5.5
- Moneyline: Michigan +152 | Oklahoma -184
- Over/Under: Over 45.5 | Under 45.5
Michigan vs Oklahoma trend to know
In Sherrone Moore’s first season, Michigan stumbled to a 1-6 record against the spread to start the year, worth keeping in mind after the Wolverines fell 17.5 points short of covering last week’s spread. Find more college football betting trends for Michigan vs Oklahoma.
How to watch Michigan vs Oklahoma
| Location | Memorial Stadium, Norman, OK |
| Date | Saturday, September 6, 2025 |
| Kickoff | 7:30 p.m. ET |
| TV | ABC |
Michigan vs Oklahoma latest injuries
Michigan vs Oklahoma weather
Monitor gametime conditions with our College football weather info.
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
