Spurs vs Bulls Prediction, Picks & Odds for Tonight’s NBA Game

The Spurs looked more cohesive with De'Aaron Fox back in the fold. Expect more of the same tonight against the Bulls.

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst
Nov 10, 2025 • 13:31 ET • 4 min read

NBA

Match starts: 1 hrs
CHI
47 %
SA
53 %
EXPERT PICK - SPREAD
San Antonio -4.5 (-105) San Antonio -4.5 (-105)
Read Analysis
De'Aaron Fox San Antonio Spurs NBA
Photo By - Imagn Images. Spurs G De'Aaron Fox (4) during his season debut.

The Chicago Bulls will try to maintain their undefeated home record as they host Victor Wembanyama and the San Antonio Spurs tonight.

The return of De'Aaron Fox seemed to spark San Antonio on Saturday, and I’m picking the visitors to cover tonight in my Spurs vs. Bulls predictions.

Keep reading for a closer look at this matchup and my free NBA picks for Monday, November 10.

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Spurs vs Bulls prediction

Spurs vs Bulls best bet: Spurs -4.5 (-105)

After starting the year 5-0, the San Antonio Spurs ran into a two-game losing streak to start November. Victor Wembanyama suddenly seemed mortal, finishing with fewer than 20 points and 10 rebounds in both games, leading to questions about whether his hot start was sustainable.

Perhaps all he needed was a little more offensive support to take some of the burden off his shoulders. That came on Saturday in the form of De’Aaron Fox, who immediately hopped back into action by scoring 24 points on 9-for-14 shooting in 31 minutes of work.

While Fox still said he was rusty coming back from surgery to repair a tendon in his left hand, having him on the court led Wembanyama to his best game since October, as he went for 18 points and 18 rebounds in the win over the New Orleans Pelicans.

The Spurs will get a good test tonight when they visit the Chicago Bulls, who are 5-0 at home.

However, Chicago has lost three of its last four games and has struggled to contain elite stars like Giannis Antetokounmpo (41 points on Friday) and Donovan Mitchell (29 points on Saturday). 

Wemby will provide a similar challenge, and with Fox to help, San Antonio is too much for Chicago to deal with tonight.

Spurs vs Bulls same-game parlay

Along with taking San Antonio to cover on the road, I’m going to parlay that with bets on two of their top players to hit their marks.

I’m taking Fox to continue scoring and Wembanyama to pick up at least 12 rebounds, something he’s already done five times this season.

Spurs vs Bulls SGP

  • Spurs -4.5
  • De'Aaron Fox Over 19.5 points
  • Victor Wembanyama Over 11.5 rebounds

Our "from downtown" SGP: Fox in the henhouse

Nikola Vucevic has come in Under tonight’s PRA total in each of his last three games, and faces a tough matchup with Wembanyama tonight. The Spurs have hit the Over in each of their last four games, and are even more likely to put up points with Fox on the court.

Spurs vs Bulls SGP

  • Spurs -4.5
  • De'Aaron Fox Over 19.5 points
  • Victor Wembanyama Over 11.5 rebounds
  • Nikola Vucevic Under 32.5 points + rebounds + assists
  • Over 237.5

Spurs vs Bulls odds

  • Spread: Spurs -4.5 (-105) | Bulls +4.5 (-115)
  • Moneyline: Spurs -180 | Bulls +150
  • Over/Under: Over 237 (-110) | Under 237 (-110)

Spurs vs Bulls betting trend to know

The Bulls have lost three of their last four games by at least six points. Find more NBA betting trends for Spurs vs. Bulls.

How to watch Spurs vs Bulls

Location United Center, Chicago, IL
Date Monday, November 10, 2025
Tip-off 8:00 p.m. ET
TV FDSN-Southwest, CHSN

Spurs vs Bulls latest injuries

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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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