Detroit may be the underdog on its own home court, but I’m taking it to win outright in my Knicks vs. Pistons predictions and NBA picks below.
Knicks vs Pistons prediction
Knicks vs Pistons best bet: Pistons moneyline (+115)
The New York Knicks have now lost three straight games, including their last two in New York. The biggest factor in this sudden slide may be the loss of Josh Hart, who's been out for five games with an ankle injury and will be missing tonight’s game, too.
The Detroit Pistons are also dealing with their own injury problems, as they’re currently playing without starting center Jalen Duren (17.9 ppg) and Tobias Harris (13.4 ppg). Detroit was still able to pick up a road win against the Cavaliers on Sunday in a victory that highlighted the team’s depth.
With the injuries on both sides, both teams will be playing a bit below their normal level, but it’s still worth noting that Detroit would likely be an outright favorite with two healthy lineups on the court. The Pistons are 12-3 at home, have a better point differential than the Knicks, and hold the second-best record in the NBA overall.
That, combined with what we’ve seen from the Knicks lately, has me wondering why Detroit shouldn’t be expected to win this game at home. Cade Cunningham continues to make the players around him look better, and the Pistons seem to have an endless line of quality players to work off their star. I’m taking the Pistons to win outright at home.

Knicks vs Pistons same-game parlay
Along with taking the Pistons to win at home, I’m also going to back the Under in my SGP tonight, as the injuries to both sides should trend the game below the total. I’ll also take Duncan Robinson to go Over 11.5 points, as he's averaging 11.6 ppg and should be among the players taking more shots to cover for the absences of Jalen Duren and Tobias Harris.
Knicks vs Pistons SGP
- Pistons moneyline
- Under 232.5
- Duncan Robinson Over 11.5 points
Our "from downtown" SGP: Cade in spades
Cunningham puts up enough volume from 3-point range to hit this target, and will likely be taking on an even bigger scoring role than normally given the current injuries for Detroit.
Knicks vs Pistons SGP
- Pistons moneyline
- Under 232.5
- Duncan Robinson Over 11.5 points
- Cade Cunningham Over 2.5 threes
Knicks vs Pistons odds
- Spread: Knicks -2.5 | Pistons +2.5
- Moneyline: Knicks -135 | Pistons +115
- Over/Under: Over 232.5 | Under 232.5
Knicks vs Pistons betting trend to know
The Knicks are 1-6 ATS over their last seven games. Find more NBA betting trends for Knicks vs. Pistons.
How to watch Knicks vs Pistons
| Location | Little Caesars Arena, Detroit, MI |
| Date | Monday, January 5, 2026 |
| Tip-off | 7:00 p.m. ET |
| TV | Peacock |
Knicks vs Pistons latest injuries
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