While the Cleveland Cavaliers are coming off a disappointing home loss to the Boston Celtics, my Cavaliers vs. Pacers predictions expect the Cavs to dominate the Indiana Pacers tonight.
Read on for my NBA picks for Monday, December 1.
Cavaliers vs Pacers prediction
Cavaliers vs Pacers best bet: Cavaliers -6.5 (-115)
The Cleveland Cavaliers head into Gainbridge Fieldhouse looking to end a three-game losing streak, and the numbers suggest they'll cover against the Indiana Pacers.
The Cavaliers rank 14th in points allowed, and their defensive muscles should lead the way tonight against a Pacers group boasting the second-worst offense in the NBA.
Both teams play at a Top-15 pace, but Indiana’s league-worst field-goal percentage typically means possessions don’t always translate into points.
Cleveland faces the challenge of playing with zero days' rest and will be without Jarrett Allen; however, its experienced backcourt gives the Cavs an edge.
Indiana has won two straight, but those victories came against teams that couldn’t score, and getting buckets hasn’t been Cleveland’s problem this season.
The Cavs’ guards should control the tempo and limit easy looks, with a supporting cast to finish off Indiana and cover the number.

Cavaliers vs Pacers same-game parlay
Donovan Mitchell is coming off an 18-point stinker against Boston, but scored more than 29 points in three of four before that.
Cleveland will want to ramp up the pace, and Indiana won’t mind at all. Missing Allen hurts the Cavs' defense, and I suspect we’ll see a high-scoring affair.
Cavaliers vs Pacers SGP
- Cavaliers -6.5
- Donovan Mitchell Over 28.5 points
- Over 234
Our "from downtown" SGP: Cavalier attitude
Pascal Siakam has scored at least 24 points in six of his previous eight games.
De’Andre Hunter has dished at least two assists in eight of his previous 11 games.
Cavaliers vs Pacers SGP
- Cavaliers -6.5
- Donovan Mitchell Over 28.5 points
- Over 234
- Pascal Siakam Over 23.5 points
- De'Andre Hunter Over 1.5 assists
Cavaliers vs Pacers odds
- Spread: Cavaliers -6.5 (-115) | Pacers +6.5 (-105)
- Moneyline: Cavaliers -260 | Pacers +210
- Over/Under: Over 234 (-110) | Under 234 (-110)
Cavaliers vs Pacers betting trend to know
The Indiana Pacers have lost the 2nd half in six of their last seven home games against the Cleveland Cavaliers. Find more NBA betting trends for Cavaliers vs. Pacers.
How to watch Cavaliers vs Pacers
| Location | Gainbridge Fieldhouse, Indianapolis, IN |
| Date | Monday, December 1, 2025 |
| Tip-off | 7:00 p.m. ET |
| TV | FDSN-Ohio, FDSN-Indiana |
Cavaliers vs Pacers latest injuries
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