Cavaliers vs Pacers Prediction, Picks & Odds for Tonight’s NBA Game

The Cavaliers will answer back after losing to Boston at home last time out. The Pacers won't have an answer for Donovan Mitchell & Co., as Cleveland covers the spread as road favorites.

Phil Naessens - Contributor at Covers.com
Phil Naessens • Betting Analyst
Dec 1, 2025 • 09:01 ET • 4 min read

NBA

Match starts: 9 hrs
IND
38 %
CLE
62 %
Read Analysis
Donovan Mitchell Cleveland Cavaliers NBA
Photo By - Imagn Images. Cavaliers G Donovan Mitchell (45) with possession.

While the Cleveland Cavaliers are coming off a disappointing home loss to the Boston Celtics, my Cavaliers vs. Pacers predictions expect the Cavs to dominate the Indiana Pacers tonight. 

Read on for my NBA picks for Monday, December 1.

Cavaliers vs Pacers prediction

Cavaliers vs Pacers best bet: Cavaliers -6.5 (-115)

The Cleveland Cavaliers head into Gainbridge Fieldhouse looking to end a three-game losing streak, and the numbers suggest they'll cover against the Indiana Pacers.

The Cavaliers rank 14th in points allowed, and their defensive muscles should lead the way tonight against a Pacers group boasting the second-worst offense in the NBA.

Both teams play at a Top-15 pace, but Indiana’s league-worst field-goal percentage typically means possessions don’t always translate into points.

Cleveland faces the challenge of playing with zero days' rest and will be without Jarrett Allen; however, its experienced backcourt gives the Cavs an edge.

Indiana has won two straight, but those victories came against teams that couldn’t score, and getting buckets hasn’t been Cleveland’s problem this season. 
The Cavs’ guards should control the tempo and limit easy looks, with a supporting cast to finish off Indiana and cover the number.

Enjoying Covers content? Add us as a preferred source on your Google account Add as a preferred source on Google

Cavaliers vs Pacers same-game parlay

Donovan Mitchell is coming off an 18-point stinker against Boston, but scored more than 29 points in three of four before that.

Cleveland will want to ramp up the pace, and Indiana won’t mind at all. Missing Allen hurts the Cavs' defense, and I suspect we’ll see a high-scoring affair. 

Cavaliers vs Pacers SGP

  • Cavaliers -6.5
  • Donovan Mitchell Over 28.5 points
  • Over 234

Our "from downtown" SGP: Cavalier attitude

Pascal Siakam has scored at least 24 points in six of his previous eight games.

De’Andre Hunter has dished at least two assists in eight of his previous 11 games. 

Cavaliers vs Pacers SGP

  • Cavaliers -6.5
  • Donovan Mitchell Over 28.5 points
  • Over 234
  • Pascal Siakam Over 23.5 points
  • De'Andre Hunter Over 1.5 assists

Cavaliers vs Pacers odds

  • Spread: Cavaliers -6.5 (-115) | Pacers +6.5 (-105)
  • Moneyline: Cavaliers -260 | Pacers +210
  • Over/Under: Over 234 (-110) | Under 234 (-110)

Cavaliers vs Pacers betting trend to know

The Indiana Pacers have lost the 2nd half in six of their last seven home games against the Cleveland Cavaliers. Find more NBA betting trends for Cavaliers vs. Pacers.

How to watch Cavaliers vs Pacers

Location Gainbridge Fieldhouse, Indianapolis, IN
Date Monday, December 1, 2025
Tip-off 7:00 p.m. ET
TV FDSN-Ohio, FDSN-Indiana

Cavaliers vs Pacers latest injuries

Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Phil Naessens
Betting Analyst

Prior to joining Covers in 2022, Phil Naessens spent 38 years as a resident tennis pro in Las Vegas, Mykonos, and Corfu, Greece. He’s the past host of the Phil Naessens Show (Armed Forces Radio), and currently hosts the Crush and Rush Tennis Podcast.

Phil is the author of the Betting 101 series (MLB, NFL, NCAAF, and Tennis) and has written for numerous publications, including Advance Local, SB Nation, FanSided, and Lenny Melnick Fantasy Sports. 

His favorite sports to bet on are tennis, MLB, WNBA, Euro men’s and women’s hoops, NCAA sports, NFL, and the NBA. Phil has numerous betting accounts in the US and Europe, and his best advice is to line shop for the best value possible.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo