MLB Home Run Predictions Today: Best HR Prop Bets, Picks, Parlay & Odds for Monday, September 22

Our MLB home run props expect big things from Rafael Devers, Nolan Arenado, and Matt Olson tonight.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Sep 22, 2025 • 09:23 ET • 4 min read
Rafael Devers San Francisco Giants
Photo By - Imagn Images. Rafael Devers in a recent game against the Diamondbacks.

It’s only a three-game slate tonight, but I’ve found some home run value. My MLB player props analysis will include Nolan Arenado, Matt Olson, and Rafael Devers. 

Best MLB home run props today

  • TEAM Arenado to hit a home run (+890)
  • TEAM Olson to hit a home run (+438)
  • TEAM Devers to hit a home run (+433)
  • 💲 +24648 parlay💲

Make your HR plays at DraftKings

Bet on your favorite home run props every day at DK, offering competitive odds and multi-HR props as well!

21+. Gambling problem? Call 1-800-GAMBLER.

HR Prop #1: Nolan Arenado to hit a home run

+890 at DraftKings

Nolan Arenado is certainly having a down year when it comes to power. He’s only clubbed 10 home runs for the St. Louis Cardinals, but there’s reason to believe he could hit No. 11 tonight. He’ll face Justin Verlander, whom he's 4-for-13 against in his career with one long ball.

Arenado had a nice weekend, collecting three hits across two games, including a double. Although his average against righties is poor compared to lefties, nearly all of Arenado’s power is against right-handed hurlers. He’s gone deep eight times. 

Verlander has trouble with the homer at home, giving up nine in 15 outings compared to four on the road.

HR Prop #2: Matt Olson to hit a home run

+438 at DraftKings

Matt Olson is one of the hottest hitters in baseball right now. He’s batting .357 in September and .400 across the last week. The slugger has seven home runs this month, and he’s gone deep 28 times overall. Perhaps not the power numbers we’ve seen from him in the past, but he still has serious pop in his bat. 

Olson has left the yard five times in his last nine contests, and he’ll be looking forward to tonight’s matchup. It’s lefty MacKenzie Gore on the hill for the Washington Nationals. Although he hasn’t taken him deep before, Olson is 5-for-20, and three of those hits were doubles. 

The slugger is batting .290 against left-handed pitchers with six homers this season as well.

HR Prop #3: Rafael Devers to hit a home run

+433 at DraftKings

Rafael Devers had a slow start to his San Francisco Giants career, but he’s begun to show exactly why they pulled off a blockbuster trade for him. The veteran is now up to 32 home runs on the year while hitting .251. He’s batting .261 at home with 17 round-trippers. 

He’ll be up against Michael McGreevy tonight, who takes the hill for the Cards. Devers is 2-for-3 lifetime against him with one home run. McGreevy has allowed six of his eight bombs to left-handed hitters like Devers. I’ll take him to crack No. 33 of the campaign in the series opener. 

Today’s HR parlay

Nolan Arenado to hit a home run

Matt Olson to hit a home run

Rafael Devers to hit a home run

Today’s most popular HR bets

  1. Shohei Ohtani, Dodgers
  2. Cal Raleigh, Mariners
  3. Kyle Schwarber, Phillies

Betting info courtesy of DraftKings

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

Pages related to this topic

Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo