Amanda Serrano vs Lucrecia Manzur Predictions, Picks & Odds for Today’s Featherweight Fight

Danny Howard - Contributor at Covers.com
Danny Howard • Betting Analyst 21+ years betting experience
Updated: Aug 21, 2026 , 08:23 AM ET • 4 min read

Amanda Serrano has 32 career knockouts to her name, and she'll make quick work of Manzur in this featherweight bout, per our boxing expert.

Amanda Serrano vs Lucrecia Manzur Boxing Picks
Photo By - Reuters Connect. Amanda Serrano (red gloves) and Katie Taylor (blue gloves) fight during the undisputed super lightweight championship boxing bout at Madison Square Garden

Amanda Serrano vs. Lucrecia Manzur takes place tonight in Temecula, CA, and will be the first title fight streamed live on TikTok. Serrano is chasing her own piece of history and enters as a massive -3000 favorite. 

Check out our free betting picks and Serrano vs. Manzur predictions for this title fight on Friday, Aug. 21.

Who will win Amanda Serrano vs Lucrecia Manzur: Serrano (-3000)

Amanda Serrano vs Lucrecia Manzur
Aug 21
Fight Prediction
Serrano to win (-3000)
Bet now at DraftKings

Serrano is a massive favorite, facing an opponent set up to take a knockout loss so she can break the knockout record for women’s boxing.

As long as Serrano stays at featherweight, she remains a devastating puncher and one of the better tactical minds in the sport. This will be too big of a jump in class for Manzur, and Serrano should dominate the fight.   

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Amanda Serrano vs Lucrecia Manzur best bet: Serrano to win Round 1-6 (+120)

Amanda Serrano vs Lucrecia Manzur
Aug 21
BEST BET
Serrano to win in rounds 1-6 (+120)
Bet now at DraftKings

Serrano is a -3000 favorite and is favored to win by knockout at -310. There is no value in a straight bet, but what appeals to me here is Manzur has been stopped in two of her four losses.

I expect Serrano to bulldoze Manzur and get a stoppage, and I can see it happening within the first six rounds. 

Covers COVERS INTEL: Serrano enters with 32 career knockouts and can become the outright women’s boxing record-holder with one more stoppage, while Manzur has already been stopped twice in four career losses

Amanda Serrano vs Lucrecia Manzur prop pick

Amanda Serrano vs Lucrecia Manzur
Aug 21 
Prop pick
Serrano to win in rounds 4-6 (+250)
Bet now at DraftKings

At +250, and considering the skill gap between these two, this could be the sweet spot that may not seem all that risky. Serrano will be pushing the pace early on, and Manzur may have absorbed enough damage where she’ll be ready to go by the midpoint. 

Amanda Serrano vs Lucrecia Manzur odds

DraftKings
Method of Victory Amanda Serrano Lucrecia Manzur
To win outright -3000 +1100
To win by KO/TKO -450 +1800
To win by points or decision +250 +2500

Odds as of August 21.

Serrano by KO/TKO is heavily favored at -310, but that reflects the enormous disparity in experience and firepower. With Serrano chasing the women’s boxing knockout record against an overmatched opponent, a stoppage is the most logical outcome. 

Amanda Serrano vs Lucrecia Manzur tale of the tape

Amanda Serrano   Lucrecia Manzur
37 Age 27
5-foot-6 Height 5-foot-2
Featherweight Weight Class Featherweight
65.5 inches Reach N/A
49-4 Record 14-4
32 Wins by KO 5

The Puerto Rican legend has more than three times as many professional fights and 32 knockouts compared to Manzur’s seven. Manzur is also taking an enormous step up in competition, while Serrano has spent more than a decade fighting at the championship level across multiple weight classes. 

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Danny Howard - Covers.com
Betting Analyst

After a decade of covering all things boxing, from recapping the sport’s biggest fights to sharing behind-the-scenes details of the sweet science, Danny found himself immersed in sports betting, focusing on the sports he knows best. As a boxing and MMA contributor with seasoned experience from growing up around each sport, he can uncover the nuances and intangibles that can make the difference between victory and defeat.

Danny’s work has been mentioned on ESPN and USA Today, and he was a featured guest on The Esportz Network podcast, where he shared his combat sports insights. He is also a published author, with his novel And Stay Down! Boxing’s Worst Comebacks available on Amazon.

Danny is always on the lookout for the best odds and props when it comes to fight night, with Draft Kings and BetMGM being his go-to sites. Danny’s approach to finding value in the theater of the unexpected hinges on the fighters' recent form, especially when considering props.

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