The Boston Bruins face elimination as they take on the Buffalo Sabres in Game 5 at KeyBank Center on Tuesday, April 28.
My top Bruins vs. Sabres predictions & NHL picks back Buffalo to deliver at home and end Boston’s season.
- UPDATE: Added prediction for who will win & goal scorer pick.
Bruins vs Sabres Game 5 prediction
Who will win Bruins vs Sabres Game 5?
Sabres: Home ice wasn’t kind to the Bruins, and this series has been a massive mismatch the past two games, with the Sabres winning both by a combined 9-2 score. The underlying numbers were just as telling, too.
Bruins vs Sabres best bet: Sabres moneyline (-155)
The gap in five-on-five play between the Buffalo Sabres and Boston Bruins at TD Garden the past two games has been astronomical, so I love the Sabres finishing the series off in Game 5.
Buffalo drove possession with a 61.9 Corsi For percentage and generated an eye-poping 68.4% of the expected goals when adjusted for score and venue at 5-on-5, and most importantly, the Sabres solved Bruins goalie Jeremy Swayman with six goals in Game 4.
Hats off to Boston for rallying to their Game 2 win after gifting away the series opener, but this has turned ugly for the Bruins with the Sabres outscoring them 9-2 over the past two games to take a commanding 3-1 lead back home to the KeyBank Center.
Enjoying Covers content? Add us as a preferred source on your Google account
Bruins vs Sabres Game 5 same-game parlay
While the Buffalo moneyline is my preference as a standalone best bet, the puck line provides a nice odds boost for this same-game parlay.
Boston hasn’t had an answer for the Tage Thompson-Alex Tuch duo, and they’ve clicked with winger Peyton Krebs for a 55.8 CF% and 63.3 xGF% at 5-on-5 while combining for 10 points during the series.
Tuch has been particularly dangerous with 2.52 expected goals and five high-danger scoring chances, with Thompson just as effective with 1.94 ixG and five HDSC, and the Bruins have also allowed the second-most goals and expected goals per 60 minutes this postseason.
Bruins vs Sabres SGP
- Sabres -1.5
- Tage Thompson Over 0.5 points
- Alex Tuch Over 0.5 points
Bruins vs Sabres Game 5 goal scorer pick
Jason Zucker (+270)
Sabres winger Jason Zucker has recorded an impressive 2.02 expected goals and seven high-danger scoring chances without finding the back of the net this series, and he’s also cemented into a middle-line role while jumping the boards with the No. 1 power-play unit.
The veteran has eight 20-goal seasons on his resume, and Zucker has also buried double-digit goals with the man advantage each of the past two years with Buffalo. He breaks through in Game 5.
Bruins vs Sabres odds for Game 5
- Moneyline: Bruins +140 | Sabres -170
- Puck Line: Bruins +1.5 (-180) | Sabres -1.5 (+145)
- Over/Under: Over 5.5 (-125) | Under 5.5 (+105)
Bruins vs Sabres trend
The Buffalo Sabres have covered the puck line in seven of their last nine games (+7.00 Units / 48% ROI). Find more NHL betting trends for Bruins vs. Sabres.
How to watch Bruins vs Sabres Game 5
| Location | KeyBank Center, Buffalo, NY |
| Date | Tuesday, April 28, 2026 |
| Puck drop | 7:30 p.m. ET |
| TV | TNT, Sportsnet |
Bruins vs Sabres latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
