The winless Houston Texans head into their Week 5 tilt against the also-winless Tennessee Titans as 6.5-point favorites after pushing the Cowboys to the edge in Week 4. Kickoff is scheduled for 1 p.m. ET at Nissan Stadium in Nashville.
Houston looked much better against Dallas, and my Texans vs. Titans predictions expect the visitors to finally grab their first victory of the season. Find out more in my NFL picks for Sunday, Oct. 11.
Texans vs Titans predictions
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Percentages courtesy of Kalshi, one of the best prediction market apps.
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Early Texans vs Titans spread pick: Texans -6.5
Play up to 55%.
A winless record through a month never looks good, but the Houston Texans are coming off one of their best performances of the season, especially offensively. C.J. Stroud threw for 347 yards and two touchdowns, while Houston kept pace with Dallas, registering 397 yards to the Cowboys' 399.
The Texans moved the ball well and led for most of the game before a late collapse. There were still issues defensively, while 13 penalties for 90 yards also proved costly. However, DeMeco Ryans' team now faces a Tennessee Titans squad that ranks near the bottom of the league in several offensive categories.
After finally finding a rhythm on Sunday, I'll back the Texans to build on that Week 4 showing and cover against Tennessee.
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Early Texans vs Titans total pick: Under 39.5
Play up to 58%.
Houston might've finally scored some points, but this still looks like a relatively low-scoring divisional matchup. The Texans are averaging 21 points per game, while Tennessee ranks near the bottom of the NFL at just 13.8.
The Titans have also been much more competitive defensively than offensively, while they rank second-last in the NFL in total yards per contest.
Even if Houston reaches the low-to-mid 20s, Tennessee may struggle to contribute enough for this game to clear this number.
Texans vs Titans odds
For help understanding Kalshi probabilities, see our odds calculator.
- Texans vs Titans spread: Texans -6.5
- Texans vs Titans moneyline: Texans 74%, Titans 26%
- Texans vs Titans Over/Under: 39.5
How to watch Texans vs Titans
- Date: Sunday, Oct. 11, 2026, 1 p.m. ET
- City: Nashville, Tenn.
- Venue: Nissan Stadium
- TV: CBS
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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