The Buffalo Bills and Las Vegas Raiders will meet at Allegiant Stadium this Sunday, Oct. 18, for a cross-conference matchup in Sin City. The total is set at 53.5 points, the highest on the slate this weekend, making it a great game to target for anytime touchdown bets!
My Bills vs. Raiders anytime touchdown scorer predictions and NFL picks highlight a mismatch in the trenches and an undervalued Las Vegas receiver facing a struggling Buffalo secondary unit.
Best Bills vs Raiders anytime touchdown picks
For help understanding Kalshi probabilities, see our odds calculator.
| Pick |  Probability |
|---|---|
 Josh Allen - NO |
45% |
 Tre Tucker |
24% |
| First TD: James Cook |
15% |
| Long shot: Cody White |
11% |
Percentages courtesy of Kalshi, one of the best prediction market apps.
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Bills touchdown pick: Josh Allen - NO
Playable to 47%.
In Week 5, Josh Allen became the first quarterback in NFL history to rush for a touchdown in each of his team's first five games of a season. That means no quarterback has ever scored a rushing touchdown in six consecutive games to begin a season.
The Raiders' run defense is allowing a league-worst 2.09 yards per carry before contact this season, which could further reduce Buffalo's incentive to tush push Allen in this matchup, too.
Raiders touchdown pick: Tre Tucker
Playable to 26%.
Tre Tucker is undersized, but that hasn't stopped Las Vegas from looking for him near the end zone early in 2026. Tucker is tied for the team lead in target% inside the 10-yard line and has played 70% of such snaps.
Tucker also has the speed to beat defenses deep. He has at least one 20+ yard reception in three of the Raiders' five games this season. Buffalo's secondary is vulnerable on the outside, and Tucker has the talent to make them pay.
First touchdown scorer pick: James Cook
Playable to 17%.
When Buffalo wins the coin toss, they like to take the ball first. When Las Vegas wins the coin toss, they like to take the ball second. Therefore, Buffalo players have more value in scoring first this weekend than Las Vegas players.
The Bills offensive line ranks fourth-best in average yards before contact through five games. The Raiders defensive line has allowed a league-worst 2.09 average yards before contact in 2026.
This is the biggest mismatch in the trenches of any NFL game in Week 6. Expect James Cook to get a couple of chances to find pay dirt if Buffalo is near the goal line.
Long-shot touchdown pick: Cody White
Playable to 12%.
Cody White has played the second-most snaps of any Las Vegas wideout each of the last two weeks. He's second among Raiders wide receivers in targets (9), first-read targets (4), and route% (53.8%) in that span.
Buffalo's secondary unit is among the worst in the NFL, ranking 28th in EPA/play and 29th in success rate against the pass this season. White is listed at 6-foot-3 and 227 pounds and has already caught three touchdowns in 2026. This is a great price in a favorable matchup.
Bills vs Raiders touchdown combo
Dalton Kincaid
Michael Mayer
Playable to 10%.
Dalton Kincaid has played every Buffalo snap inside the 10-yard line this season, and he's played 78.3% of the team's red-zone snaps, the highest usage on the team. Only Khalil Shakir has run more red-zone routes for the Bills, and no tight end has more targets than Kincaid in that area of the field.
Michael Mayer has played 90% of the Raiders' snaps inside the 10-yard line in 2026 and run a route on 85.7% of such snaps.
If you're looking for a long-shot way to root for some tight ends to find the end zone, this is good value at Kalshi.
- TD picks: 3-2, +9.72 units
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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