The Notre Dame Fighting Irish are in a great position for the College Football Playoff right now, but an upset in the Big 12 title game could knock the Irish out of the desired postseason.
Marcus Freeman knows he needs to make a statement against the Stanford Cardinal to protect his postseason hopes.
Tonight's Notre Dame vs. Stanford predictions and college football picks recognize the easiest way for the Irish to enjoy some complimentary headlines after a late kickoff on Saturday, November 29.
Kickoff is set for 10:30 p.m. ET from Stanford Stadium, with the game airing on ESPN.
Notre Dame vs Stanford prediction
Notre Dame vs Stanford best bet: Jeremiyah Love Over 135.5 rushing yards (-114)
It is not that complicated a scenario that would knock Notre Dame out of the College Football Playoff. If BYU beats Texas Tech in the Big 12 title game, especially if Alabama also wins the SEC, then the Irish would be left off the bracket.
Their best-case scenario in that moment would be to hope some folks think Notre Dame should get in ahead of Oklahoma
Burgeoning Jeremiyah Love’s Heisman campaign in recent weeks has served that goal. The Playoff selection committee will be endeared by a Heisman contender in a gold helmet.
Fourth in the Heisman odds in no small part because he has cleared this prop in four of his last five games, Love should see plenty of opportunities late on Saturday night because Stanford’s offense will simply struggle to stay on the field.
Until Love has filled his stat line, expect Notre Dame to funnel him the ball, both in pursuit of his slim Heisman hopes and in an effort to strengthen the Irish Playoff case.
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Notre Dame vs Stanford same-game parlay
Obviously, Notre Dame covers the 32.5-point spread in this scenario. Mostly, the thought here is that the Irish defense scores for the third game in a row. Defensive scores always better the chance of an Over, no matter how wretched one offense may be.
Notre Dame vs Stanford SGP
- Jeremiyah Love Over 135.5 rushing yards
- Over 49.5
- Stanford team total Under 7.5
Our deep-ball SGP: Endless Love
Could CJ Carr throw for 250+ yards late on Saturday night? Absolutely. Stanford’s defense struggles greatly against the pass. But as Notre Dame has blown out three straight opponents, Carr has never been asked to run up the score. The Irish rushing game does that by default on its own.
Instead, Carr has thrown for 218, 212, and 49 yards in the last three games.
Notre Dame vs Stanford SGP
- Jeremiyah Love Over 135.5 rushing yards
- Over 49.5
- Stanford team total Under 7.5
- CJ Carr Under 223.5 passing yards
Notre Dame vs Stanford game predictions
Notre Dame vs Stanford moneyline prediction
Marcus Freeman has lost to Stanford before.
Including that, he has lost as a hefty favorite three times as Notre Dame’s head coach, but recognizes that the Irish have made it a habit of improving as the season goes along in each of Freeman’s four years in charge of the program.
Notre Dame vs Stanford spread prediction
Notre Dame has covered the spread in each of its last three games, despite being favored by at least 31 points in two of those.
In fact, the Irish are 4-1-1 against the spread as at least three-score favorites this season.
Notre Dame vs Stanford Over/Under prediction
Notre Dame has cashed the Over the last two times it was favored by at least 31 points, each within the last few weeks.
Credit the Irish defense, forcing short drives from opponents and thus getting the ball back to an explosive offense.
Notre Dame vs Stanford odds
- Spread: Notre Dame -32.5 | Stanford +32.5
- Moneyline: Notre Dame -20000 | Stanford +3500
- Over/Under: Over 49.5 | Under 49.5
Notre Dame vs Stanford trend to know
Notre Dame has beaten Stanford by a combined score of 105-30 in the last two matchups, covering the spread in both games as well as single-handedly cashing each Over. Find more college football betting trends for Notre Dame vs Stanford.
How to watch Notre Dame vs Stanford
| Location | Stanford Stadium, Stanford, CA |
| Date | Saturday, November 29, 2025 |
| Kickoff | 10:30 p.m. ET |
| TV | ESPN |
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