Baylor vs SMU Prediction, Picks & Odds for September 6 — College Football Week 2

Josh Cameron had only two catches in Week 1 but still cleared his Week 2 total of 49.5. Expect more touches and more yards from the wide out vs. SMU.

JD Yonke - Betting Analyst at Covers.com
JD Yonke • Betting Analyst
Sep 4, 2025 • 12:00 ET • 4 min read

NCAAF

Match starts: 45 hrs
SMU
66 %
BAY
34 %
Read Analysis
Josh Cameron Baylor Bears NCAAF
Photo By - Imagn Images. Baylor Bears wide receiver Josh Cameron (34) carries the ball as Auburn Tigers defensive end Amaris Williams (10) defends during the second half at McLane Stadium.

One of the top matchups in the college football world in Week 2 features the Baylor Bears visiting the SMU Mustangs in a quality non-conference matchup. 

See why I’m bullish on the Bears in my Baylor vs. SMU predictions and college football picks for Saturday, September 6.

Baylor vs SMU prediction

Baylor vs SMU best bet: Josh Cameron Over 49.5 receiving yards (-114)

Bookmakers expect points in bunches in a game with a total of 65.5 as of the time of this writing. Considering the Baylor Bears’ 38-24 loss to Auburn in the opener, it’s understandable. 

Baylor’s offense wasn’t at fault in the loss, generating 23 first downs and 483 total yards. Quarterback Sawyer Robertson is one of the sport’s most effective quarterbacks in the country and got off to a hot start, throwing for 419 yards on 8.7 yards per attempt with three touchdowns and no interceptions. 

He spread the ball around as four different receivers topped 50 yards. Surprisingly, last year’s leading receiver, Josh Cameron, was fourth on that list with just two receptions for 54 yards. Expect a quick bounce back for the top receiving target on one of the nation’s most prolific offenses. 

Cameron was electric when he had the ball, forcing three missed tackles on just two touches. He’s a big play waiting to happen and should find room to work against an SMU defense that has a ton of turnover after last year’s surprisingly stingy results. 

Cameron has gone Over 49.5 receiving yards in nine of his last 14 games and will make that 10 of 15 in Week 2.

Baylor vs SMU same-game parlay

It’s not time to throw Baylor in the trash just yet after the Auburn loss, as that’s a quality SEC team that underplayed its metrics a year ago but was due for a bounce back. 

That being said, the defense showed vulnerabilities up front, especially defending the QB rush (Jackson Arnold had 137 rushing yards and two scores).

That’ll be tough to fix in one week, especially going up against another terrific dual-threat in Kevin Jennings, who should contribute more with his legs this season for an offense missing Brashard Smith’s 18 touchdowns from a year ago. 

Our deep-ball SGP: Dual-threat QBs

  • Robertson's legs will contribute after being injured in 2024
  • SMU lost three defensive line starters and two linebacks from last year’s defense. 

Baylor vs SMU odds

  • Spread: Baylor +2.5 | SMU -2.5
  • Moneyline: Baylor +115 | SMU -135
  • Over/Under: Over 65 | Under 65

Baylor vs SMU trend to know

Baylor has covered the spread in eight of its last 13 games.  Find more college football betting trends for Baylor vs SMU.

How to watch Baylor vs SMU

Location Gerald J. Ford Stadium, Dallas, TX
Date Saturday, September 6, 2025
Kickoff 12:00 p.m. ET
TV The CW Network

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Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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JD Yonke
Betting Analyst

JD is a diehard college football fan with five years of experience writing betting and fantasy content for publications such as SportsGrid, Fantasy Points, Fantrax, and Devy Watch. An avid reader, he uses his inclination to look at things with an exhausting and in-depth, analytic viewpoint combined with a love for statistics and metrics to form a well-rounded handicapping approach.

e's an integral member of the niche (but growing!) college fantasy football community, twice traveling to Canton, OH for the Fantasy Football Expo as a member of the CFF King's Classic drafting squad. His specialization in college football DFS and prop betting taught him that there are exploitable markets to be found and that narrowing your focus is integral to being a profitable bettor.

A lifelong Californian who grew up playing baseball, basketball, football, and lacrosse, he's glad to share a passionate love for sports with this wonderful community.

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