Best NBA Parlays Today: Top Same-Game Parlays & Combos for Thursday, Oct. 22

Aisha Quiñones - Betting Analyst at Covers
Aisha Quiñones • Betting Analyst 12+ years betting experience
Updated: Oct 22, 2026 , 02:18 PM ET • 4 min read

A Sixers duo anchors tonight's action, and we're backing a high-octane performance with Tyrese Maxey orchestrating the offense and Joel Embiid making plays.

Tyrese Maxey Joel Embiid Philadelphia 76ers Isaiah Hartenstein Oklahoma City Thunder NBA
Photo By - Reuters Connect. Tyrese Maxey Joel Embiid Philadelphia 76ers Isaiah Hartenstein Oklahoma City Thunder NBA

Today's NBA doubleheader parlays feature custom three-leg combos, combining spread picks, game totals, and player props for tonight's action.

With Tyrese Maxey and Isaiah Hartenstein headlining the slate, we've rounded up our favorite combos for each matchup.

Check out the NBA parlays and detailed analysis below, and browse our free NBA picks for more ways to attack tonight's games.

NBA parlays at a glance (Thursday, Oct. 22)

Matchup & time Combo & analyst
Cavaliers vs. 76ers
7 p.m.
76ers moneyline
Tyrese Maxey Over 2.5 threes
Joel Embiid Over 3.5 assists
Combo: 4.66x
Quinn Allen
Nuggets vs. Thunder
9:30 p.m.
Under 236.5
Aaron Gordon 6+ rebounds
Isaiah Hartenstein 3+ assists 
Combo: 7.41x
Geoff Clark

Picks courtesy of Polymarket, one of our best prediction market apps.

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Cavaliers vs 76ers

    Combo: 4.66x

    • 76ers moneyline
    • Tyrese Maxey Over 2.5 threes
    • Joel Embiid Over 3.5 assists

    I'm eyeing two of Philly's stars to make their presence felt tonight. 

    Although Tyrese Maxey went just 2-for-9 from deep in the opener, the guard is a high-volume shooter who averaged 3.1 makes on 8.6 long-range attempts per game last season. The Cavs aren't great at defending the perimeter, and point guards averaged 2.7 threes against them in '25-26. 

    Embiid dished out six dimes against New York and averaged just below 3.5 assists per contest vs. Cleveland last season. The Sixers' starting five is showing solid chemistry, and with Embiid no longer the primary scoring focal point, I like him to have another productive night facilitating the offense and creating more open looks in my Cavaliers vs. 76ers predictions.

    Nuggets vs Thunder

      Combo: 7.41x

      • Under 236.5
      • Aaron Gordon 6+ rebounds
      • Isaiah Hartenstein 3+ assists 

      Denver forward Aaron Gordon and Oklahoma City big Isaiah Hartenstein give this combo two prop legs that fit naturally with a slower, more physical game.

      If possessions stay concentrated in the half court, Gordon should spend plenty of time battling around the rim and chasing misses instead of sprinting back in transition. Hartenstein benefits for a different reason.

      More structured possessions should keep the ball in his hands as a facilitator, especially when Denver forces OKC to work deeper into the shot clock.

      That’s why the props and total fit together so well. Gordon can clean the glass, Hartenstein can create from the high post, and neither offense needs to play fast for either leg to cash in my Nuggets vs. Thunder predictions.

      More NBA picks

      Want to build a bigger card? These Covers roundups cover every bet type for today's games:

      Check the NBA injury report and compare numbers across basketball betting sites before finalizing today's picks.

      All of today’s matchups are also on the NBA scores and matchups page, and the full pick archive lives in free NBA picks.

      Odds are correct at the time of publishing and are subject to change.
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      Aisha Quiñones - Covers
      Betting Analyst

      Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

      Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

      Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

      Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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