It’s a battle at the top of the East tonight, as the No. 1 Detroit Pistons host the surging New York Knicks, who are tied with Boston for the second-best record in the conference.
While New York seeks its ninth straight win, my Knicks vs. Pistons predictions and NBA picks for Friday, February 6 target the total in what should be a high-scoring affair.
Knicks vs Pistons prediction
Knicks vs Pistons best bet: Over 222.5 (-110)
This game features two teams in the Top 8 in scoring in the NBA.
The New York Knicks are averaging 118.2 points per game on the year, but they’ve been even more potent during this win streak. Their 134-127 OT victory over Denver last time out was the third time in the last four games they’ve tallied at least 127 points.
The Detroit Pistons boast a Top 4 defense to go with scoring 117.5 points per game (T-8th), but they’ve been leaking of late. They were just dumped by the Wizards 126-117 Thursday night and have allowed at least 121 points in three of their last four.
Detroit might also be down big man Jalen Duren, who left the Wizards game with a knee injury. He’s listed as day-to-day.
The Pistons will be playing the second half of a back-to-back, and that usually means big points. They have gone Over the total in six of the eight games they’ve played on no rest this season, the best Over success rate in the NBA.
Enjoying Covers content? Add us as a preferred source on your Google account
Knicks vs Pistons same-game parlay
Cade Cunningham scored 30 in the loss to Washington, making it three times in the last four games he’s topped the 26.5 scoring line set for Friday.
His counterpart Jalen Brunson dropped 42 in the 2OT win over Denver, and he generally lights up Detroit, going for at least 27 points in seven of the last nine games.
Knicks vs Pistons SGP
- Over 222.5
- Cade Cunningham Over 26.5 points
- Jalen Brunson Over 26.5 points
Our "from downtown" SGP: Anunoby comes up aces
OG Anunoby has quietly slid into New York’s premier secondary scorer behind Brunson. He’s got a 17.5-point scoring line Thursday, a figure he’s crossed five straight games, topping 20+ four times.
Karl-Anthony Towns is the league’s leading rebounder and has been on a tear recently, pulling down at least 12 boards in five straight games, including a pair of 20+ rebound outings.
Knicks vs Pistons SGP
- Over 222.5
- Cade Cunningham Over 26.5 points
- Jalen Brunson Over 26.5 points
- OG Anunoby Over 17.5 points
- Karl-Anthony Towns Over 11.5 rebounds
Knicks vs Pistons odds
- Spread: Knicks -1.5 | Pistons +1.5
- Moneyline: Knicks -115 | Pistons -105
- Over/Under: Over 222.5 | Under 222.5
Knicks vs Pistons betting trend to know
New York has covered the spread in eight straight games. Find more NBA betting trends for Knicks vs. Pistons.
How to watch Knicks vs Pistons
| Location | Little Caesars Arena, Detroit, MI |
| Date | Friday, February 6, 2026 |
| Tip-off | 7:30 p.m. ET |
| TV | Prime Video |
Knicks vs Pistons latest injuries
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
