Knicks vs Cavaliers Prediction, Picks & Odds for Tonight’s NBA Game

James Harden shows Cavaliers fans why Cleveland acquired him in a key Eastern Conference showdown against the Knicks.

Phil Naessens - Contributor at Covers.com
Phil Naessens • Betting Analyst
Feb 24, 2026 • 08:04 ET • 4 min read

NBA

Match starts: 10 hrs
NY
37 %
CLE
63 %
EXPERT PICK - PROP
James Harden o18.5  Points Scored (-115) James Harden o18.5 Points Scored (-115)
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James Harden Cleveland Cavaliers NBA
Photo By - Reuters Connect. Cavaliers guard James Harden (1) gestures to his team during a play against the Thunder.

The Cleveland Cavaliers return home to Rocket Arena to host the New York Knicks in a battle between two Eastern Conference powerhouses.

The Cavs acquired James Harden for games like this, and my Knicks vs. Cavaliers predictions expect a strong offensive showing. 

Read on for my NBA picks for Tuesday, February 24.

Knicks vs Cavaliers prediction

Knicks vs Cavaliers best bet: James Harden Over 18.5 points (-115)

James Harden is averaging 18.7 points per game with the Cleveland Cavaliers, shooting an efficient 50% from inside the arc and 47% from downtown, and he has a terrific matchup tonight. 

The New York Knicks don’t consistently trap high, and if they choose to guard him straight up, they’ll see a healthy diet of mid-range jumpers, pull-up threes, and layups.

Games like tonight are why the Cavs traded for Harden. They’ve lost two straight to the Knicks, but Harden is a wily and creative scorer, and I’m betting on a vintage scoring night from the veteran guard. 

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Knicks vs Cavaliers same-game parlay

Karl-Anthony Towns leads the NBA in double-doubles and only needs a typical 22-10-3 line to clear his PRA combo prop.

Landry Shamet is averaging 13.7 points in 27 minutes since February 1, making 10 points a very reachable number.

Knicks vs Cavaliers SGP

  • James Harden Over 18.5 points
  • Karl-Anthony Towns Over 33.5 points + rebounds + assists
  • Landry Shamet Over 9.5 points

Our "from downtown" SGP: Cleveland rocks the house

Cleveland is deeper, healthier, and playing its best basketball at home. They are 8-2 straight up over their last 10 games and have more offensive firepower with Harden in the lineup.

Knicks vs Cavaliers SGP

  • James Harden Over 18.5 points
  • Karl-Anthony Towns Over 33.5 points + rebounds + assists
  • Landry Shamet Over 9.5 points
  • Cavaliers moneyline

Knicks vs Cavaliers odds

  • Spread: Knicks +4 (-105) | Cavaliers -4 (-115)
  • Moneyline: Knicks +150 | Cavaliers -180
  • Over/Under: Over 231.5 (-110) | Under 231.5 (-110)

Knicks vs Cavaliers betting trend to know

The Cleveland Cavaliers have hit the Moneyline in 14 of their last 17 games (+10.35 Units / 20% ROI). Find more NBA betting trends for Knicks vs. Cavaliers.

How to watch Knicks vs Cavaliers

Location Rocket Arena, Cleveland, OH
Date Tuesday, February 24, 2026
Tip-off 7:30 p.m. ET
TV Peacock

Knicks vs Cavaliers latest injuries

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Phil Naessens
Betting Analyst

Prior to joining Covers in 2022, Phil Naessens spent 38 years as a resident tennis pro in Las Vegas, Mykonos, and Corfu, Greece. He’s the past host of the Phil Naessens Show (Armed Forces Radio), and currently hosts the Crush and Rush Tennis Podcast.

Phil is the author of the Betting 101 series (MLB, NFL, NCAAF, and Tennis) and has written for numerous publications, including Advance Local, SB Nation, FanSided, and Lenny Melnick Fantasy Sports. 

His favorite sports to bet on are tennis, MLB, WNBA, Euro men’s and women’s hoops, NCAA sports, NFL, and the NBA. Phil has numerous betting accounts in the US and Europe, and his best advice is to line shop for the best value possible.

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