Cavaliers vs Pistons Computer Picks: Our Best Player Prop Projections for Game 1

Aisha Quiñones - Betting Analyst at Covers
Aisha Quiñones • Betting Analyst 12+ years betting experience
Updated: May 5, 2026 , 03:37 PM ET • 4 min read

The Eastern Conference semifinals are here & we've analyzed Game 1 between the Cleveland Cavaliers and Detroit Pistons, highlighting key player prop angles and comparing them to the latest market lines.

Cade Cunningham Donovan Mitchell Detroit Pistons Cleveland Cavaliers NBA
Photo By - Reuters Connect. Detroit Pistons guard Cade Cunningham (2) throws a pass beside Cleveland Cavaliers guard Donovan Mitchell (45) in the fourth quarter.

Our NBA player prop projections are ready for Game 1 of the Eastern Conference semifinals matchup between the Cleveland Cavaliers and Detroit Pistons, with the model highlighting several high-value spots.

By analyzing the data against current market lines, we’ve identified where the strongest edges exist.

These Cavaliers vs. Pistons predictions are driven by numbers instead of guesswork.

If you’re building your card, here are the model’s top NBA picks for Tuesday, May 5.

Cavaliers vs Pistons computer picks for Game 1

Cavaliers Cavaliers Pistons Pistons
Mitchell u25.5 points 
-115
Cunningham o26.5 points
-125
Mobley o8.5 rebounds
-102
Duren o10.5 rebounds 
-115
Harden o2.5 3-pointers 
-130
Robinson o2.5 3-pointers 
-105

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Cavaliers Game 1 computer picks

Donovan Mitchell Under 25.5 points (-115)

Projection: 23.3 points

This season, opposing starting shooting guards have shot just 27.6% from three against the Detroit Pistons (the second-worst mark in the league) making it a difficult matchup for Donovan Mitchell to clear his points prop in Game 1.

🔥 Bet mitchell Now at bet365!

Evan Mobley Over 8.5 rebounds (-102)

Projection: 8.59 rebounds

The Cleveland Cavaliers have led the league with 15.0 offensive rebounds per game over their last five outings, and Evan Mobley made his presence felt on the glass against the Raptors — a trend he’ll look to carry into the Eastern Conference semifinals.

🔥 Bet mobley Now at bet365!

James Harden Over 2.5 3-pointers (-130)

Projection: 2.61 3-pointers

This season, opposing starting point guards have averaged 6.2 three-point attempts per game against the Pistons — the 10th-most in the league — setting up a favorable spot for James Harden to thrive from deep. When Harden gets it going, the Cavaliers tend to follow, so expect him to set the tone early and clear the Over on this prop.

🔥 Bet harden Now at bet365!


Pistons Game 1 computer picks

Cade Cunningham Over 26.5 points (-125)

Projection: 28.7 points

Cade Cunningham is on a tear, averaging 32.2 points over his last five games — a jump of 8.2 from his season average.

The matchup with Cleveland only adds fuel to the fire, as opposing starting point guards have shot a league-high 41.4% from three against the Cavaliers this year, setting Cunningham up nicely to boost his scoring from beyond the arc in Game 1.

🔥 Bet cunningham Now at bet365!

Jalen Duren Over 10.5 rebounds (-115)

Projection: 12.06 rebounds

Detroit ranks third in the league with 13.0 offensive rebounds per game, and as the Pistons’ top presence on the glass, Jalen Duren will look to assert himself early — battling Evan Mobley and Jarrett Allen by owning the boards and setting the tone inside.

🔥 Bet duren Now at bet365!

Duncan Robinson Over 2.5 3-pointers (-105)

Projection: 3.22 3-pointers

Duncan Robinson cleared the Over in five of seven games during the opening round against Orlando, but this matchup brings a different kind of challenge. Cleveland’s defense is far more disciplined on the perimeter, closing out hard and limiting clean looks from deep, which will put added pressure on Robinson to find space.

If Detroit wants to keep pace, they’ll need Robinson to get going early from beyond the arc and knock down shots against a Cavaliers defense that won’t give him many easy opportunities.

🔥 Bet robinson Now at bet365!

How to watch Cavaliers vs Pistons Game 1

Location Little Caesars Arena, Detroit, MI
Date Tuesday, May 5, 2026
Tip-off 7 p.m. ET
TV Peacock/NBC

Not intended for use in MA.
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Aisha Quiñones - Covers
Betting Analyst

Hailing from Harlem, New York, Aisha Quiñones joined Covers in 2024 after an illustrious career with several other major media outlets. A proud Johnnie, after graduating from the Big East basketball powerhouse St. John's University, Quiñones earned her bachelor's degree in sport management and journalism, then obtained her master's degree in media studies from The New School.

Over a span of 12+ years, Quiñones has built her portfolio as a writer, dipped her toe into on-camera work, and also been behind the scenes in producing sports content.

Despite being a New Yorker, Quiñones has always been a lifelong Los Angeles Lakers fan thanks to her mom's joy of watching Kobe Bryant play — so much of a fan to the point that Quiñones named her toy poodle after the late-great legend.

Her hometown roots stay true to her MLB and WNBA choice in teams, as a Yankees and Liberty fan, due to her uncle and grandmother's love for the sports throughout her childhood.

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