The Toronto Blue Jays open the second half as -135 favorites at home against the Chicago White Sox, handing the ball to rookie Spencer Miles opposite left-hander Anthony Kay.
Toronto’s bats get a favorable draw against a lefty who has struggled away from home, and Vladimir Guerrero Jr. headlines my card as he rounds back into form.
Read on for my White Sox vs. Blue Jays predictions and MLB picks for this Friday, July 17 matchup.
White Sox vs Blue Jays predictions
White Sox vs Blue Jays best bet: Vladimir Guerrero Jr. Over 1.5 total bases (+120)
The tide should turn for Vladimir Guerrero Jr. soon. He came out of the All-Star break with a rested back, and he was already swinging it well before the layoff.
Over his last three games before the break, Vladdy hit .273 with a homer and four RBI, and that three-run blast in San Diego was a big confidence boost.
Now he draws a mediocre lefty in Anthony Kay, who carries a 5.94 ERA on the road this season. Vladdy is 1-for-2 lifetime against Kay with a home run, offering a great opportunity to get back on track.
I’d play this bet to +110.
COVERS INTEL: Guerrero is trading groundballs for line drives lately. His 41.7% line-drive rate in July is a 21.9% jump from his June mark, which should fuel some extra-base hits.
White Sox vs Blue Jays same-game parlay (SGP)
For the same-game parlay, I’m backing the Toronto Blue Jays at home behind a pitcher I trust. Rookie Spencer Miles gets a real shot at a full-time rotation spot, and he’s earned it with a 2.85 ERA and a 1.10 WHIP that stack up with anyone.
I’ll pair the moneyline with two bats built to punish Chicago White Sox starter Anthony Kay. George Springer Over 1.5 total bases and Vladdy Over 1.5 total bases double down on my read that this road-weary lefty is there for the taking.
White Sox vs Blue Jays SGP
- Blue Jays moneyline
- George Springer Over 1.5 total bases
- Vladimir Guerrero Jr. Over 1.5 total bases
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White Sox vs Blue Jays home run pick: George Springer (+510)
Keep an eye on George Springer in this one. Despite a subpar season overall, Springer has been Toronto’s sharpest hitter against southpaws, posting an .810 OPS in 81 at-bats.
He’s long been considered a lefty killer, and I have little faith in Kay’s stuff, especially with the left-hander pitching on the road.
I’d keep this one to a quarter unit.
- Best bets: 7-3, +3.63 units
- SGPs: 2-9, -0.56 units
- HR picks: 2-9, -0.53 units
White Sox vs Blue Jays odds
- Moneyline: Chicago +115 | Toronto -135
- Run line: Chicago +1.5 (-170) | Toronto -1.5 (+145)
- Over/Under: Over 8.5 | Under 8.5
White Sox vs Blue Jays trend
Anthony Kay carries a 5.94 ERA on the road this season versus 3.06 at home, and he’s pitching at Rogers Centre on Friday. Find more MLB betting trends for White Sox vs. Blue Jays.
How to watch White Sox vs Blue Jays and game info
| Location | Rogers Centre, Toronto, ON |
| Date | Friday, 7-17-2026 |
| First pitch | 7:15 p.m. ET |
| TV | Sportsnet |
| White Sox starting pitcher | Anthony Kay (6-4, 4.23 ERA) |
| Blue Jays starting pitcher | Spencer Miles (4-1, 2.85 ERA) |
White Sox vs Blue Jays latest injuries
White Sox vs weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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