Shohei Ohtani Picks, Predictions & Best Bets for Game 1 of the World Series

Although his playoff batting average isn't the prettiest, Ohtani has left the yard five times in 10 postseason games. He'll hit No. 6 on Friday.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Oct 23, 2025 • 09:55 ET • 4 min read
Los Angeles Dodgers two-way player Shohei Ohtani (17) reacts to his solo home run against the Milwaukee Brewers.
Photo By - Imagn Images. Los Angeles Dodgers two-way player Shohei Ohtani (17) reacts to his solo home run against the Milwaukee Brewers.

The 2025 World Series begins on Friday evening as the Los Angeles Dodgers and Toronto Blue Jays face off for baseball’s ultimate prize. 

I’ve dug through the Shohei Ohtani odds to find the best way to wager on the Dodgers' superstar in Game 1.

Read more for my MLB picks for Friday, October 24. 

Shohei Ohtani prop pick

Shohei Ohtani best bet: Anytime home run (+230 at BetMGM)

Ohtani hasn’t swung it particularly well in the 2025 postseason, hitting just .220 across 41 at bats. But, if there’s one thing he is doing, it’s hitting bombs. The two-way superstar has gone deep five times in these playoffs after cracking 55 regular-season dingers. 

Ohtani played hero in Game 4 of the NLCS against the Milwaukee Brewers as the Dodgers completed the sweep. He left the yard three times and also tossed six scoreless innings on the mound.

The Jays have yet to announce who will start Game 1 of the World Series, but Ohtani has six career homers against their pitching staff. 

Shohei Ohtani same-game parlay

Over 1.5 total bases

Over 0.5 RBI

Dodgers moneyline

If Ohtani is going to have a banner night at the dish, the chances are he’s driving guys in. He has nine RBI in the playoffs, and two against the Blue Jays this year.

The Dodgers have been a dominant force in these playoffs, losing just one game. Blake Snell is on the hill in Game 1, and he's posted a 0.86 ERA in the playoffs. The Blue Jays are also hitting just .227 against Snell across 66 ABs.

How to watch Dodgers vs Blue Jays and Game 1 info

Location Rogers Centre, Toronto, ON
Date Friday, October 24, 2025
First pitch 8:00 p.m. ET
TV FOX

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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