The Chicago Cubs welcome the Cincinnati Reds to Wrigley Field for a weekend set, trading at 64% on Polymarket.
My Reds vs. Cubs predictions break down why the hosts will come out on top in a high-scoring game.
Read my free MLB picks for Friday, Aug. 28 below.
Who will win Reds vs Cubs today: Cubs moneyline (64%)
The Chicago Cubs own the best offense in baseball (5.19 runs per game), and they’ll be licking their chops today when they face Cincinnati Reds starter Rhett Lowder.
The right-hander owns a massive 5.14 xERA (10th percentile) and .266 xBA (16th percentile), while ranking in the 15th percentile in pitching run value.
The Cubs have been on fire at the dish this week, led by Ian Happ, who’s sporting an insane 1.335 OPS with 10 RBI. As a club, Chicago leads the majors in runs (39), SLG (.512), and OPS (.858) over the last seven days.
Take the Cubs up to 67%.
COVERS INTEL: The Cubs are batting .301 (third in MLB) with a .373 wOBA (second in MLB) against the sinker, which is Lowder’s most utilized pitch (29.2%).
Reds vs Cubs Over/Under pick: Over 8.5 (50%)
We know Lowder has been lousy, but David Peterson has been just as bad for Chicago.
The southpaw has a 4.84 xERA and .271 xBA, with a pitching run value in the ninth percentile. The Reds’ offense is also much more respectable against left-handed pitching, as they sit eighth in MLB in OPS vs. southpaws (.731).
The Cubs have cashed the Over in eight of Peterson’s last 10 appearances, while the Over is 2-0 in their two prior games against Lowder this season.
The Over is the play up to 52%.
Reds vs Cubs home run prediction: Ian Happ (19%)
What a week it’s been for Happ.
The Cubs outfielder leads the majors with 10 RBI over that span while batting .350 with a ridiculous 1.335 OPS and three dingers to boot.
Happ has hit eight of his 23 home runs against either the sinker or the slider — Lowder’s two main offerings.
Happ’s on fire and we’re getting a great price on him to go yard again. Play him up to 21%.
- ML/RL bets: 8-7, +0.06 units
- Over/Under bets: 7-8, -1.57 units
Reds vs Cubs weather
Wrigley Field will see clear skies with temperatures in the mid-70s and light winds pushing in from right field.
Reds vs Cubs odds
- Moneyline: Cincinnati (37¢) | Chicago (64¢)
- Run line: Cincinnati +1.5 (56¢) | Chicago -1.5 (47¢)
- Over/Under: Over 8.5 (46¢) | Under 8.5 (55¢)
Reds vs Cubs trend
The Cubs have covered the run line in 28 of their last 45 games (+16.10 Units / 31% ROI). Find more MLB betting trends for Reds vs. Cubs.
How to watch Reds vs Cubs and game info
| Location | Wrigley Field, Chicago, IL |
| Date | Friday, Aug. 28, 2026 |
| First pitch | 2:20 p.m. ET |
| TV | ESPN Unlimited |
| Reds starting pitcher | Rhett Lowder (5-8, 5.13 ERA) |
| Cubs starting pitcher | David Peterson (7-7, 5.17 ERA) |
Reds vs Cubs latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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