The Seattle Mariners and Houston Astros close their three-game series tonight at Daikin Park on Sunday Night Baseball, with Bryan Woo facing Hunter Brown in the rubber match.
Houston is a -129 moneyline favorite, while Seattle is +121 with the total set at 7.5.
Our Mariners vs. Astros predictions are backing the Astros behind Brown's contact suppression. Read on for our MLB picks for Sunday, Aug. 16.
For more on this game, read Colby Marchio's Mariners vs. Astros props.
Who will win Mariners vs Astros today: Astros moneyline (-120)
The Houston Astros are my moneyline pick because their biggest offensive strength attacks Bryan Woo's clearest weakness.
Houston owns an .859 OPS against right-handed pitching at home over the last 30 days, the best mark in MLB over that span.
Woo has allowed a 43.5% hard-hit rate, ranking in the 13th percentile, while his four-seamer has been hit hard 44.3% of the time.
Hunter Brown provides the opposite matchup, holding opponents to an 85.7-mph average exit velocity and 36.2% hard-hit rate.
I'd play to -140.

Mariners vs Astros Over/Under pick: Under 7.5 (+101)
The Seattle Mariners' recent offensive form runs directly into Brown's greatest strength.
Seattle owns just a .660 OPS over the last seven days, and Brown has been one of baseball's best pitchers at limiting any type of hard contact.
Brown ranks in the 95th percentile in hard-hit rate, allowing just a 36.2% mark with an 85.7-mph average exit velocity and .334 xSLG.
Woo has also limited barrels to 6.7%, despite allowing more general hard contact. Seattle's matchup with Brown makes it difficult for both offenses to contribute enough to clear 7.5.
I'd play to -118, or +110 at 7.
Mariners vs Astros home run prediction: Yordan Alvarez (+276)
Woo throws his four-seamer and sinker on 65.8% of his pitches, and Yordan Alvarez has destroyed both offerings. He carries a .796 xSLG, .516 xwOBA, and 59.1% hard-hit rate against four-seamers, plus a .584 xSLG and .439 xwOBA against sinkers.
If Alvarez gets anything competitive, then this matchup sets up well for him.
- ML/RL bets: 43-42, +2.1 units
- Over/Under bets: 48-37, +12.58 units
Mariners vs Astros weather
Houston is forecast to remain around 95 degrees near first pitch, but Daikin Park's roof guidelines call for closure when the temperature or heat index exceeds 77 degrees, so I expect a climate-controlled matchup.
Mariners vs Astros odds
- Moneyline: Mariners +120 | Astros -130
- Run line: Mariners +1.5 | Astros -1.5
- Over/Under: Over 7.5 | Under 7.5
Mariners vs Astros trend
The Astros have covered the run line in 29 of their last 50 games (+10.75 Units / 17% ROI). Find more MLB betting trends for Mariners vs. Astros.
How to watch Mariners vs Astros and game info
| Location | Daikin Park, Houston, TX |
| Date | Sunday, August 16, 2026 |
| First pitch | 7:20 p.m. ET |
| TV | NBC |
| Mariners starting pitcher | Bryan Woo (8-8, 4.15 ERA) |
| Astros starting pitcher | Hunter Brown (3-2, 2.68 ERA) |
Mariners vs Astros latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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