Cubs vs Giants Prediction, Picks & Odds — Thursday, August 28

Our MLB betting picks see few runs coming across at Oracle Park today when Shota Imanaga and the Cubs take on Logan Webb and the Giants.

Quinn Allen - Betting Analyst at Covers.com
Quinn Allen • Betting Analyst
Aug 28, 2025 • 09:10 ET • 4 min read

MLB

Match starts: 4 hrs
SF
45 %
CHC
55 %
EXPERT PICK - TOTAL
u7.0 (+100)
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Shota Imanaga Cubs MLB
Photo By - Imagn Images. Chicago Cubs SP Shota Imanaga in MLB action.

The Chicago Cubs and San Francisco Giants wrap up a three-game set this afternoon at Oracle Park. 

It’s Shota Imanaga vs. Logan Webb on the mound, and I’ll explain in my Cubs vs. Giants predictions why I see value in the Under with a pair of studs facing off. 

Keep reading for my MLB picks for Thursday, August 29. 

Cubs vs Giants prediction

Cubs vs Giants best bet: Under 7 (+100)

Wednesday’s contest was a high-scoring one, with the San Francisco Giants securing a 12-3 victory as they lit up Colin Rea. But today, it’s definitely a pitchers’ duel. Both Shota Imanaga and Logan Webb are having spectacular seasons for their respective teams. 

Imanaga has an 8-6 record and 3.03 ERA this year, and he’s compiled a 2.33 ERA in August. The Japanese left-hander hasn’t given up more than three earned runs in a single start this month.

Imanaga is typically lights out for the Chicago Cubs, and he was dominant when last seen, only allowing two earned across seven frames versus the Brewers. 

As for Webb, he’s also throwing the ball extremely well. The right-hander is 12-9 with a 3.13 ERA.

His ERA lowers to 2.77 at home, and Webb has allowed a mere one earned run across his last two appearances. 

The total may be low here, but I don’t see a lot of runs being scored. Both guys will do their thing on the bump. 

Cubs vs Giants same-game parlay (SGP)

Webb has always been a strikeout pitcher, and 2025 has been no different. He’s racked up 180 Ks in 166 2/3 innings of work. At home, Webb has struck out 94 in 87 2/3 frames.

The veteran has cashed the Over in punchouts in three of his last five outings, and two of them were at Oracle Park. 

While there aren't many hitters in this Cubs lineup who have had success against Webb, Ian Happ is one of them. The 31-year-old is 4-for-11 lifetime with a pair of doubles and a home run. 

Cubs vs Giants odds

  • Moneyline: Chicago +109 | San Francisco -121
  • Run line: Chicago +1.5 | San Francisco -1.5
  • Over/Under: Over 7 | Under 7

Cubs vs Giants trend

The Giants have hit the Under in 37 of their last 62 games at home (+11.25 Units / 16% ROI). Find more MLB betting trends for Cubs vs. Giants.

How to watch Cubs vs Giants and game info

Location Oracle Park, San Francisco, CA
Date Thursday, August 28, 2025
First pitch 3:45 p.m. ET
TV MARQ, NBCSBA
Cubs starting pitcher Shota Imanaga
(8-6, 3.03 ERA)
Giants starting pitcher Logan Webb
(12-9, 3.13 ERA)

Cubs vs Giants latest injuries

Cubs vs Giants weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Quinn Allen - Covers
Betting Analyst

Quinn Allen is an experienced sports journalist from Vancouver, Canada who fell in love with sports by the time he could walk. He proceeded to play high-level baseball and soccer growing up and eventually played college baseball in the United States.

After his career ended, Quinn received his broadcast journalism degree from BCIT and has since written for many sports publications including ClutchPoints, Gino Hard, and RG, where he plies his trade as a writer and editor.

Quinn's favorite team is Chelsea FC and he'd like to watch a match at Stamford Bridge one day. He loves to bet on NBA player props and encourages others to bet responsibly and not chase losses.

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