Deontay Wilder and Derek Chisora finally come to blows as two of the premier heavyweights of the last decade face off in the twilight of their careers.
Chisora is the favorite at -190 while former champion Wilder is a +150 underdog. My Wilder vs. Chisora predictions and betting picks side with the favorite for this bout.
Wilder vs Chisora prediction and pick
- My fight prediction: Chisora moneyline (-190 at DraftKings)
- My best bet: Chisora by KO/TKO/DQ (+135 at DraftKings)
Fight analysis
The decline of Deontay Wilder has been dramatic and difficult to ignore.
After compiling 10 defenses of his portion of the heavyweight title in a reign that may not age well, Wilder’s aura, confidence, and overall mentality appeared to unravel following his grueling trilogy with Tyson Fury.
Derek Chisora, meanwhile, remains one of the most reliable and troublesome veterans the heavyweight division has seen. Now both in their 40s, each man enters this fight with a sense of finality.
Since his 2022 loss to Fury, Chisora has rebounded with wins over former contenders and continues to look like a credible, durable opponent.
He's coming off a commanding victory over Otto Wallin and remains as awkward, aggressive, and physically demanding as ever.
Despite the punishment he has absorbed throughout his career, Chisora continues to demonstrate solid durability, improved defensive awareness, and the ability to push opponents over the distance.
The same cannot be said for Wilder. Once a feared champion, his offense has become increasingly one-dimensional, relying almost entirely on a telegraphed right hand.
Since 2020, Wilder has gone 2-4 and looked labored even in victory, needing seven rounds to stop an overmatched Tyrrell Anthony Herndon in a fight that was expected to end much earlier.
Chisora is still competitive in this late stage of his career. His pressure and infighting should make it difficult for Wilder to find the space needed to set up his right hand.
While Wilder’s power always gives him a chance, his struggles on the inside and apparent decline in confidence are significant concerns.
Chisora is the pick.
Best best analysis
With Wilder’s offense increasingly reduced to isolated right-hand attempts, Chisora should be able to close the distance and consistently disrupt his rhythm.
Wilder’s best chance lies in catching Chisora on the way in, but his timing and trigger appear diminished, and Chisora’s durability gives him room to absorb and continue pressing forward.
As Chisora applies sustained pressure, targeting the body and working in close quarters, the fight should gradually shift in his favor.
If Wilder is unable to establish distance or regain confidence early, there is a real possibility he fades under the constant pressure.

Deontay Wilder vs Derek Chisora odds
| Method of victory | Deontay Wilder | Derek Chisora |
|---|---|---|
| Win outright | +150 | -190 |
| Win by KO/TKO | +225 | +135 |
| Win by points or decision | +800 | +280 |
| Draw | +1800 | +1800 |
Odds courtesy of DraftKings as of April 2.
Deontay Wilder vs Derek Chisora tale of the tape
| Wilder | Chisora | |
|---|---|---|
| 40 | Age | 42 |
| 6-foot-7 | Height | 6-foot-2 |
| Heavyweight | Weight Class | Heavyweight |
| 83 inches | Reach | 74 inches |
| 44-4 | Record | 36-13 |
| 43 | Wins by KO | 23 |
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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