Doo ho Choi vs Daniel Santos Predictions, Picks & Odds

Danny Howard - Contributor at Covers.com
Danny Howard • Betting Analyst 21+ years betting experience
Updated: May 16, 2026 , 09:00 AM ET • 4 min read

This is the co-main event of Saturday's UFC Fight Night, and our Choi vs Santos predictions expect Santos to put his opponent to bed.

 Daniel Santos (red gloves) reacts after the fight against Joosang Yoo.
Photo By - Reuters Connect. Daniel Santos (red gloves) reacts after the fight against Joosang Yoo.

Two high-octane featherweights are primed for an explosion when Doo ho Choi faces Daniel Santos in a fight between two offensive-minded battlers in the co-main event of this weekend’s UFC Fight Night.

UFC odds have pegged Santos as the -175 favorite, and Choi as a +135 underdog. While both fighters are coming off statement wins, my Choi vs. Santos predictions back the favorite.

Choi vs Santos fight prediction: Santos moneyline (-175)

Allen vs Costa
Apr XX • UFC Fight Night
Fight Prediction
Santos to win (-175)
Bet now at BET99

There’s no doubt Doo Ho Choi has looked improved since returning from his four-year layoff, but those wins came against lower-tier opposition. Santos represents a major step up in both skill and danger.

He brings the more complete offensive toolkit and the kind of power needed to trouble Choi, who tends to brawl and absorb punishment to stay in striking distance.

While Choi’s size and toughness will keep him competitive early, Santos’ pressure and heavier shots should gradually take over. 

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Choi vs Santos best bet: Santos to win by KO/TKO/DQ (+275)

Allen vs Costa
Apr XX • UFC Fight Night
Best bet
Santos to win by KO/TKO/DQ (+275)
Bet now at BET99

It’s going to take a lot of firepower from Santos to put Choi down, so it’s good that he’s shown that his power can carry over into the later rounds, as we saw in his most recent win over JooSang Yoo.

As the pace and damage begin to wear on Choi, Santos will find an opportunity to put him out late in the fight. My best bet is Santos wins by knockout. 

Covers COVERS INTEL: Before ending his four-year layoff, Choi was knocked out in back-to-back fights.

Doo ho Choi vs Daniel Santos odds

Bet99
Method of Victory Choi Santos
To win outright +140 -175
To win by KO/TKO +350 +285
To win by decision +475 +225
To win by submission +1200 +540
Total rounds Over 4.5
-140
Under 4.5
+110

Odds as of 5-13.

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Doo ho Choi vs Daniel Santos tale of the tape

Choi   Santos
35 Age 31
5-foot-9 Height 5-foot-7
Featherweight Weight Class Featherweight
70 inches Reach 67 inches
16-4 Record 14-2
13 Wins by KO 7
1 Wins by submission 2

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Danny Howard - Covers.com
Betting Analyst

After a decade of covering all things boxing, from recapping the sport’s biggest fights to sharing behind-the-scenes details of the sweet science, Danny found himself immersed in sports betting, focusing on the sports he knows best. As a boxing and MMA contributor with seasoned experience from growing up around each sport, he can uncover the nuances and intangibles that can make the difference between victory and defeat.

Danny’s work has been mentioned on ESPN and USA Today, and he was a featured guest on The Esportz Network podcast, where he shared his combat sports insights. He is also a published author, with his novel And Stay Down! Boxing’s Worst Comebacks available on Amazon.

Danny is always on the lookout for the best odds and props when it comes to fight night, with Draft Kings and BetMGM being his go-to sites. Danny’s approach to finding value in the theater of the unexpected hinges on the fighters' recent form, especially when considering props.

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